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Senior CRA - Home or Office Based

060739_1573726435

About the role

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Senior Clinical Research Associate (SCRA)
Location: Office based in Johannesburg or home based in South Africa
At ICON, it's our people that set us apart.
As a global provider of drug development solutions, our work is serious business. But that doesn't mean you can't have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry. Are you one of them?
As a Senior Clinical Research Associate at ICON, you'll work within a large-scale, fast-paced environment alongside a close-knit team of highly qualified CRAs to identify, select, initiate and close-out investigational sites for clinical studies in phases II - III, ensuring adherence to applicable regulations and principles of ICH-GCP. We pride ourselves on our amazing company culture, where we work as one team to achieve industry-leading results.
The role
  • Working independently and proactively to coordinate all necessary activities required to set up and monitor a study, completing accurate study status reports and maintaining study documentation
  • Submission of protocol, consent documents for ethics/IRB approval and assist in preparing regulatory submissions as requested
  • Participate in preparing and reviewing study documentation and feasibility studies for new proposals as required
  • Managing sponsor generated queries efficiently and responsible for study cost effectiveness
  • Dependent on level of experience you may assist in training and mentoring less experienced CRA's and/or manage CRA's working on international projects

What you need
  • 18 months+ of monitoring experience in phase I-III trials as a CRA
  • Availability to travel (plane or car) 60%
  • Knowledge of ICG GCP guidelines and expertise to review and evaluate medical data
  • Excellent communication and interpersonal skills, both written and verbal enabling you to deal with queries in a timely manner
  • Ability to produce accurate work to tight deadlines within a pressurized environment

Why join us?
Ongoing development is vital to us, and as a Senior CRA you will have the opportunity to progress your career, with the potential to move into other related areas to enhance your skill set. Our benefits package is competitive, our scope is international and we genuinely care about our people and their success.
List #1

Day in the life

Nurse and patient
Understanding Roles in a Clinical Trial: Sponsors, CROs, and Sites

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Publish date

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What Sponsors, CROs, and Sites Each Do Clinical research brings together many organisations, each with a specific role in delivering a clinical trial. For those new to the industry, the relationsh

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Learn how clinical trials are delivered by understanding the roles of sponsors, CROs, and sites.

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From Lab Bench to Program Leadership: Sinéad McKeon's Career at ICON

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Content type

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Publish date

02/05/2026

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Building expertise through diverse roles and continuous learning Sinéad McKeon's career at ICON demonstrates how scientific training can evolve into strategic leadership. Now a Senior Manager in Lab

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Discover how a career can evolve from hands on lab work to program management in this interview with Sinéad McKeon.

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Shaping the Future of Patient Safety: A Conversation with Hassan Aljobori

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Content type

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Publish date

02/05/2026

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Shaping the Future of Patient Safety At ICON, patient safety is the foundation of everything we do. Hassan Aljobori, Director of Pharmacovigilance, shares his journey through nine years of growth

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Hassan shares his career journey, advice for building a career in pharmacovigilance, and what sets ICON apart as an employer.

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