JUMP TO CONTENT
Shortlist
search jobs Search
About the role ICON and you Application Process Day in the life Who we are

Senior CRA - Home or Office Based

060739_1573726435

About the role

This vacancy has now expired. Please click here to view live vacancies.
Senior Clinical Research Associate (SCRA)
Location: Office based in Johannesburg or home based in South Africa
At ICON, it's our people that set us apart.
As a global provider of drug development solutions, our work is serious business. But that doesn't mean you can't have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry. Are you one of them?
As a Senior Clinical Research Associate at ICON, you'll work within a large-scale, fast-paced environment alongside a close-knit team of highly qualified CRAs to identify, select, initiate and close-out investigational sites for clinical studies in phases II - III, ensuring adherence to applicable regulations and principles of ICH-GCP. We pride ourselves on our amazing company culture, where we work as one team to achieve industry-leading results.
The role
  • Working independently and proactively to coordinate all necessary activities required to set up and monitor a study, completing accurate study status reports and maintaining study documentation
  • Submission of protocol, consent documents for ethics/IRB approval and assist in preparing regulatory submissions as requested
  • Participate in preparing and reviewing study documentation and feasibility studies for new proposals as required
  • Managing sponsor generated queries efficiently and responsible for study cost effectiveness
  • Dependent on level of experience you may assist in training and mentoring less experienced CRA's and/or manage CRA's working on international projects

What you need
  • 18 months+ of monitoring experience in phase I-III trials as a CRA
  • Availability to travel (plane or car) 60%
  • Knowledge of ICG GCP guidelines and expertise to review and evaluate medical data
  • Excellent communication and interpersonal skills, both written and verbal enabling you to deal with queries in a timely manner
  • Ability to produce accurate work to tight deadlines within a pressurized environment

Why join us?
Ongoing development is vital to us, and as a Senior CRA you will have the opportunity to progress your career, with the potential to move into other related areas to enhance your skill set. Our benefits package is competitive, our scope is international and we genuinely care about our people and their success.
List #1

Day in the life

Female using a laptop to search for jobs
Improving Your Visibility in the Clinical Research Job Market

Teaser label

Career Progression

Content type

Blogs

Publish date

11/26/2025

Summary

How Clinical Research Job Seekers Can Enhance Their Applications Finding the right role in clinical research has become increasingly competitive as organisations continue to expand their study por

Teaser label

Discover the search terms recruiters use most often and practical steps that can help candidates strengthen their visibility.

Read more
Headshot of female
Site Engagement at ICON: Daniela's Journey

Teaser label

Inside ICON

Content type

Blogs

Publish date

11/14/2025

Summary

Building Bridges in Clinical Research:        Daniela's Journey at ICON Daniela Rocco's career in clinical research has been driven by something straightforward but powerful: connection. From her e

Teaser label

Explore a site engagement career at ICON through liaison Daniela Rocco's journey.

Read more
Female portrait
A Career in Patient Safety: Karina's Journey at ICON

Teaser label

Our People

Content type

Blogs

Publish date

11/14/2025

Summary

Karina Espinoza's Journey at ICON Karina Espinoza's career in pharmacovigilance didn't begin with a grand plan. It started with a practical problem during her final year of a PhD in epidemiology, a

Teaser label

Explore a pharmacovigilance career at ICON through Karina Espinoza's story.

Read more
View all

Similar jobs at ICON

Senior CRA

Salary

Location

Argentina, Buenos Aires

Location

Buenos Aires

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

We are currently seeking a Senior Clinical Research Associate (CRA) to join our diverse and dynamic team. As a Senior CRA at ICON Plc, you will play a critical role in overseeing and managing clinical

Reference

JR137651

Expiry date

01/01/0001

Simone Chan

Author

Simone Chan
Simone Chan

Author

Simone Chan
Read more Shortlist Save this role
Read more Shortlist Save this role
Study Start up Associate

Salary

Location

Brazil, Sao Paulo

Location

Sao Paulo

Remote Working

Office Based

Business Area

ICON Strategic Solutions

Job Categories

Study Start Up

Job Type

Permanent

Description

We are currently seeking a Study Start Up Associate I to join our diverse and dynamic team. As a Study Start Up Associate I at ICON, you will play a pivotal role in facilitating the initiation of clin

Reference

JR139762

Expiry date

01/01/0001

Bruna Duarte

Author

Bruna Duarte
Bruna Duarte

Author

Bruna Duarte
Read more Shortlist Save this role
Read more Shortlist Save this role
Study Start Up CRA 2

Salary

Location

Argentina, Buenos Aires

Location

Buenos Aires

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

We are currently seeking a Senior Clinical Research Associate (CRA) to join our diverse and dynamic team. As a Senior CRA at ICON Plc, you will play a critical role in overseeing and managing clinical

Reference

JR138832

Expiry date

01/01/0001

Tulio Sanquiz

Author

Tulio Sanquiz
Tulio Sanquiz

Author

Tulio Sanquiz
Read more Shortlist Save this role
Read more Shortlist Save this role
Financial/Commercial Analyst II - 9 Month Contract

Salary

Location

Ireland, Dublin

Department

Full Service - Corporate Support

Full Service - Commercial Solutions

Location

Dublin

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Accounting & Finance

Job Type

Contractor

Description

We are currently seeking a Financial/Commercial Analyst II to join our diverse and dynamic team. As a Financial Analyst II at ICON, you will play a significant role in supporting advanced financial pl

Reference

JR134535

Expiry date

01/01/0001

Clodagh Finnegan

Author

Clodagh Finnegan
Clodagh Finnegan

Author

Clodagh Finnegan
Read more Shortlist Save this role
Read more Shortlist Save this role
Project Manager, Feasibility Site Activation

Salary

Location

Mexico, Mexico City

Location

Mexico City

Remote Working

Office or Home

Business Area

ICON Full Service & Corporate Support

Job Categories

Project Management

Job Type

Permanent

Description

Role Summary:Accountable for driving and accelerating the activation of global investigative sites in line with, or ahead of, the study's contractual timelines, within budgeted resources, with quality

Reference

JR139756

Expiry date

01/01/0001

Florencia Borello Taiana

Author

Florencia Borello Taiana
Florencia Borello Taiana

Author

Florencia Borello Taiana
Read more Shortlist Save this role
Read more Shortlist Save this role
Site Management Associate

Salary

Location

Italy, Milan

Department

Real World Solutions

Location

Milan

Remote Working

Office or Home

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

We are currently seeking a Site Management Associate II to join our diverse and dynamic team. As a Site Management Associate II at ICON, you will play a vital role in supporting the management and mon

Reference

JR136784

Expiry date

01/01/0001

Sophie Bingham

Author

Sophie Bingham
Sophie Bingham

Author

Sophie Bingham
Read more Shortlist Save this role
Read more Shortlist Save this role
View Jobs

Browse popular job categories below or search all jobs above