JUMP TO CONTENT

Clinical Trial Manager - CNS/Rare Diseases (Home-based)

JR065031

About the role

This vacancy has now expired. Please click here to view live vacancies.

At ICON, it's our people that set us apart.

As a global provider of drug development solutions, our work is serious business. But that doesn't mean you can't have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry! Are you one of them?

At ICON, we have an incredible opportunity for an expert Clinical Trial Manager to join the team in the US.

The Role:

The Clinical Trial Manager is responsible for the delivery of all clinical aspects of the study. The CTM oversees the clinical portion of the budget, develops monitoring plans & tools, trains CRAs, drives enrolment and study start-up activities, reviews trip reports, implements corrective and preventative action plans, liaises with the Sponsor, vendors & cross-functional teams, identifies & mitigates risks that may impact clinical delivery, and provides reporting & metrics on all clinical activities. The CTM will also participate in Sponsor, Investigator and bid defense meetings.

What you need:

  • 4 year degree or equivalent combination of education & experience
  • Demonstrated ability to drive the clinical deliverables of a study
  • Subject matter expertise in CNS and/or Rare Diseases
  • Prior monitoring experience is preferred
  • Ability to travel up to 20%
  • Fluent in local language - both written & verbal

Why join us?

Other than working with an outstanding team of ambitious people, we also offer a very competitive benefits package. This varies from country to country so a dedicated recruiter will discuss this with you at interview stage.

We care about our people as they are the key to our success. We provide an open and friendly work environment where we empower people and provide them with opportunities to develop their long term career.

Ongoing development is vital to us, and as a Clinical Trial Manager, you will have the opportunity to progress your career, with the potential to move into other related areas to improve your skillset. Our benefits package is competitive, our scope is international and we sincerely care about our people and their success.

ICON is an equal opportunity employer and committed to providing a workplace free of any discrimination or harassment.

EOE race/color/religion/sex/sexual orientation/gender identity/disability/vet/national origin

List #1

Day in the life

Izabella's Journey Back to ICON

Teaser label

Our People

Content type

Blogs

Publish date

01/26/2026

Summary

Sometimes the best way to recognise what you have is to experience life without it. For Izabella Grimaldi, a Clinical Research Associate II based in Brazil, that realisation came after seven months wo

Teaser label

Izabella shares what makes our culture, leadership, and opportunities worth coming back for.

Read more
Asian female looking through microscope in lab
Understanding CRA, CTA, and SMA Roles in Clinical Research

Teaser label

Industry

Content type

Blogs

Publish date

01/20/2026

Summary

Understanding the Difference Between CRA, CTA, and SMA Clinical research job titles can be confusing, particularly for those new to the industry. Acronyms such as CRA, CTA and SMA appear frequentl

Teaser label

This guide explains the differences, responsibilities, and how each role supports clinical trial delivery.

Read more
video job interview
Interviewing at ICON

Teaser label

Inside ICON

Content type

Blogs

Publish date

01/05/2026

Summary

Interviewing at ICON: What to Expect Applying for a new role can feel uncertain, particularly when recruitment processes use digital tools or assessments that may be unfamiliar. At ICON, we want ca

Teaser label

Learn what to expect when interviewing at ICON, and how hiring decisions are always made by people.

Read more
View all

Similar jobs at ICON

Project Manager, Imaging and Cardiac

Salary

Location

US, Blue Bell (ICON)

Department

Full Service - Development & Commercialisation Solutions

Location

Boston

Cary

Chicago

Lexington

Los Angeles

Portland

Salt Lake City

San Antonio

Whitesboro

Raleigh

Winston-Salem

Knoxville

Charlotte

Mt. Pleasant

Hickory

Rocky Mount

New York

Bristol

Wilmington

Salisbury

Downers Grove

McFarland

Blue Bell

Lenexa

Piedmont

Rochester

Long Beach

Remote Working

Office or Home

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Project Management

Job Type

Permanent

Description

We are currently seeking a Project Manager, Imaging to join our diverse and dynamic team. As a Project Manager, Imaging at ICON, you will be responsible for managing the planning, execution, and deliv

Reference

JR141514

Expiry date

01/01/0001

Kris Costello

Author

Kris Costello
Read more Shortlist Save this role
Senior Clinical Research Associate - Cardio Medical Device - US

Salary

Location

United States of America

Location

Multiple US Locations

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

To support 1 study in the cardiovascular/electrophysiology medical device space.The ideal candidate will have cardiovascular medical device monitoring experience- however, cardiovascular/electrophysio

Reference

JR142914

Expiry date

01/01/0001

Jamie Pruitt

Author

Jamie Pruitt
Read more Shortlist Save this role
Senior Clinical Research Associate - Cardio Medical Device - US

Salary

Location

United States of America

Location

Multiple US Locations

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

To support 1study in the cardiovascular/electrophysiology medical device space.The ideal candidate will have cardiovascular medical device monitoring experience- however, cardiovascular/electrophysiol

Reference

JR142912

Expiry date

01/01/0001

Jamie Pruitt

Author

Jamie Pruitt
Read more Shortlist Save this role
Clinical Research Associate - Oncology - Pennsylvania

Salary

Location

Pennsylvania

Location

Pennsylvania

Philadelphia, PA

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

What You Will Be Doing:Serve as the primary point of contact between investigational sites and the sponsorConduct all types of site visits, including selection, initiation, routine monitoring, and clo

Reference

JR142769

Expiry date

01/01/0001

Jamie Pruitt

Author

Jamie Pruitt
Read more Shortlist Save this role
View Jobs

Browse popular job categories below or search all jobs above