JUMP TO CONTENT

Clinical Trial Manager - CNS/Rare Diseases (Home-based)

JR065031

About the role

This vacancy has now expired. Please click here to view live vacancies.

At ICON, it's our people that set us apart.

As a global provider of drug development solutions, our work is serious business. But that doesn't mean you can't have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry! Are you one of them?

At ICON, we have an incredible opportunity for an expert Clinical Trial Manager to join the team in the US.

The Role:

The Clinical Trial Manager is responsible for the delivery of all clinical aspects of the study. The CTM oversees the clinical portion of the budget, develops monitoring plans & tools, trains CRAs, drives enrolment and study start-up activities, reviews trip reports, implements corrective and preventative action plans, liaises with the Sponsor, vendors & cross-functional teams, identifies & mitigates risks that may impact clinical delivery, and provides reporting & metrics on all clinical activities. The CTM will also participate in Sponsor, Investigator and bid defense meetings.

What you need:

  • 4 year degree or equivalent combination of education & experience
  • Demonstrated ability to drive the clinical deliverables of a study
  • Subject matter expertise in CNS and/or Rare Diseases
  • Prior monitoring experience is preferred
  • Ability to travel up to 20%
  • Fluent in local language - both written & verbal

Why join us?

Other than working with an outstanding team of ambitious people, we also offer a very competitive benefits package. This varies from country to country so a dedicated recruiter will discuss this with you at interview stage.

We care about our people as they are the key to our success. We provide an open and friendly work environment where we empower people and provide them with opportunities to develop their long term career.

Ongoing development is vital to us, and as a Clinical Trial Manager, you will have the opportunity to progress your career, with the potential to move into other related areas to improve your skillset. Our benefits package is competitive, our scope is international and we sincerely care about our people and their success.

ICON is an equal opportunity employer and committed to providing a workplace free of any discrimination or harassment.

EOE race/color/religion/sex/sexual orientation/gender identity/disability/vet/national origin

List #1

Day in the life

Headshot of male
25 Years in Clinical Operations at ICON: Ricardo Cortizo Justo Q&A

Teaser label

Our People

Content type

Blogs

Publish date

04/08/2026

Summary

Ricardo Cortizo Justo, Director of Clinical Operations and Site Head for Paris at ICON plc, recently marked an exceptional milestone of 25 years with the organisation. Over the course of his career, R

Teaser label

Ricardo shares insights from 25 years at ICON, covering clinical operations, leadership, and career development.

Read more
Heartbeat vitals on monitor
Central Monitoring vs On Site Monitoring

Teaser label

Industry

Content type

Blogs

Publish date

04/03/2026

Summary

Understanding Central Monitoring vs On Site Monitoring Monitoring is a core component of clinical trial oversight. It ensures that studies are conducted in line with the protocol, that data is re

Teaser label

Learn the difference between central monitoring and on site monitoring and how both support patient safety and data quality.

Read more
middle aged male wearing shirt
Francis' Journey back to ICON

Teaser label

Our People

Content type

Blogs

Publish date

03/26/2026

Summary

Why Francis returned to ICON: building a long-term career in clinical research Francis Kayamba is a Clinical Research Associate based in Johannesburg, South Africa. He first joined ICON in February

Teaser label

Francis Kayamba shares what drew him back to ICON and how the sponsor-embedded model works.

Read more
View all

Similar jobs at ICON

Manager, Clinical Operations

Salary

Location

Korea, Seoul

Location

Seoul

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Operations Management

Job Type

Permanent

Description

As a Manager, Clinical Operations at ICON, you will oversee the execution of clinical trials, ensuring that they are conducted efficiently, on time, and in compliance with regulatory requirements.What

Reference

JR148510

Expiry date

01/01/0001

Jennifer Kim

Author

Jennifer Kim
Read more Shortlist Save this role
Clinical Research Associate

Salary

Location

Taiwan, Taipei

Location

Taipei

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

We are currently seeking a Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate II at ICON, you will play a pivotal role in designing and analyzing cli

Reference

JR147203

Expiry date

01/01/0001

Sandy Tang

Author

Sandy Tang
Sandy Tang

Author

Sandy Tang
Read more Shortlist Save this role
Supervisor, Investigator Payments

Salary

Location

India, Bangalore

Department

Full Service - Corporate Support

Location

Bangalore

Chennai

Bengaluru

Remote Working

Hybrid

Business Area

ICON Full Service & Corporate Support

Job Categories

Accounting & Finance

Job Type

Permanent

Description

We are currently seeking a Supervisor, Investigator Payments to join our diverse and dynamic team. As a Supervisor, Investigator Payments at ICON, you will play a key role in managing and overseeing t

Reference

JR144597

Expiry date

01/01/0001

Puja Jaiswal

Author

Puja Jaiswal
Read more Shortlist Save this role
Regulatory Affairs Manager (CMC author)

Salary

Location

UK, Reading

Location

Frankfurt

Warsaw

Barcelona

Reading

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Drug / Device Regulatory Affairs

Job Type

Permanent

Description

Regulatory Affairs manager (CMC author) - Homebased in UK, Poland, Spain or Germany We are seeking a highly motivated and qualified regulatory CMC author/writer for the Global Regulatory Affairs CMC &

Reference

JR143467

Expiry date

01/01/0001

Patrick Hale

Author

Patrick Hale
Read more Shortlist Save this role
Senior Clinical Trial Associate

Salary

Location

UK, Reading

Location

Reading

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

We are currently seeking a Senior Clinical Trial Assistant (CTA) to join our diverse and dynamic team. As a Senior CTA at ICON Plc, you will play a key role in supporting the management and execution

Reference

JR148246

Expiry date

01/01/0001

Elisabeth Trivic Read more Shortlist Save this role
View Jobs

Browse popular job categories below or search all jobs above