JUMP TO CONTENT

Principal Clinical System Lead

  1. UK
2025-119086
  1. Clinical Trial Support
  2. ICON Strategic Solutions
  3. Remote

About the role

Principal Clinical System Lead - Homebased in the UK

As a Principal Clinical System Lead, working as a Decentralized Clinical Trials (DCT) Lead, exclusively assigned and embedded within a Pharmaceutical Company, you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.


What you will be doing:

 

Supporting the Sponsor’s eCOA clinical systems:

  • Take leadership role in eCOA project implementation
  • Lead study-specific eCOA technology deployment and management strategies for internal Global Integrated Clinical Trial Data Services stakeholders and externally across functions and service providers
  • Participate and collaborate with key process partners (e.g. Clinical Supplies, Biostatistics, Vendor Management, Procurement) in the sourcing, evaluation and audit/qualification of eCOA vendors
  • Collaborate with Global Development Office (GDO) Training & Communications group to define and maintain a training strategy for technologies
  • Act as the sponsor eCOA SME and project manager for study deployment projects
  • Lead study teams in development of study-specific user requirements specifications documents and user acceptance testing (UAT) protocols and execution. Ensure Good Documentation Practices are followed
  • Provide support to study teams to resolve eCOA issues during the conduct of the study
  • Collaborate with study teams during the protocol development process to understand requirements for IRT technologies
  • Effectively manage operational delivery with eCOA service providers; collect issues and trends from study teams; proactively work with Vendor Management and eCOA vendors for issue resolution and prevention
  • Collaborate internally and with eCOA service providers to implement standards on both system design and data reporting
  • Ensure the availability and delivery of training programs for relevant internal staff
  • Collaborate with and supports other teams by streamlining data flow between eCOA and other GDO systems (e.g. CTMS, Data Warehouse, Clinical Gateway, Clinical Supplies Management System)
  • Ensure trust through transparency in communication and individual actions; ensure outcomes are organizationally driven rather than individually driven; promote collaborative organizational success
  • Develop strategies to prioritize and deliver eCOA related initiatives in coordination with multiple internal departments
  • Direct activities of eCOA vendors, ensuring compliance with specifications and the oversight of timelines and budgets
  • Coordinate evaluation and impact assessment of changes in the eCOA landscape and makes recommendations for actions
  • Provide support to teams on audit-related issues for eCOA services
  • Ensure audit and inspection observations are evaluated and remediated in conjunction with the study team
  • Provide guidance and training to internal team members, when needed

What do you need to have?

  • 8+ years of relevant experience in a Clinical Research technology-related role within the Pharmaceutical, CRO, or technology vendor industries.
  • Experience with technology evaluation, deployment, and project management.
  • Strong knowledge / experience with eCOA systems and their function within clinical trials.
#LI-PH1

What ICON can offer you:

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

  • Various annual leave entitlements
  • A range of health insurance offerings to suit you and your family’s needs
  • Competitive retirement planning offerings to maximise savings and plan with confidence for the years ahead
  • Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being
  • Life assurance
  • Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others



Visit our careers website to read more about the benefits of working at ICON: https://careers.iconplc.com/benefits

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know through the form below.

https://careers.iconplc.com/reasonable-accommodations

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

List #1

Day in the life

A person using a pipette
Eliminating outsourcing confusion with ICON's new framework

Teaser label

Inside ICON

Content type

Blogs

Publish date

01/26/2023

Summary

The CRO market has seen an unmistakable uplift in demand for its services in recent years. The call for personalised medicine, pricing pressures, and increasing complexity in clinical trials are j

Teaser label

The CRO market has seen an unmistakable uplift in demand for its services in recent years.

Read more
A picture of holographic images coming out of an iPad
Are remote decentralised clinical trials the future?

Teaser label

Inside ICON

Content type

Blogs

Publish date

10/03/2022

Summary

In traditional clinical trials, patients must attend regular check-ins at hospitals or clinics but fully remote decentralised clinical trials (DCTs) and hybrid trials limit this by replacing the in-pe

Teaser label

In traditional clinical trials, patients must attend regular check-ins at hospitals or clinics. This is subject to change with an increase in decentralised clinical trials (DCTs).

Read more
A picture of a scientist working on an experiment
What are the four phases of a clinical trial?

Teaser label

Inside ICON

Content type

Blogs

Publish date

05/22/2022

Summary

Having enjoyed steady growth over the last several years, it’s predicted that the global clinical trials market will hit a value of $65.2 billion by 2025, and around 58% of this can be attributed to r

Teaser label

Have you ever wondered what's involved in a clinical trial? In this blog post, we take you through each distinct phase.

Read more
View all

Similar jobs at ICON

IHCRA

Salary

Location

Australia, Sydney

Department

Clinical Monitoring

Location

Sydney

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

We are currently seeking an IHCRA (In-House Clinical Research Associate) to join our diverse and dynamic team. As an IHCRA at ICON, you will play a pivotal role in supporting the execution and managem

Reference

JR129759

Expiry date

01/01/0001

Krisztina Auth Read more Shortlist Save this role
CTA

Salary

Location

Brazil

Department

Clinical Operations Roles

Location

Brazil

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

As a CTA  you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-116323

Expiry date

01/01/0001

Tulio Sanquiz

Author

Tulio Sanquiz
Read more Shortlist Save this role
In-House CRA

Salary

Location

Brazil

Department

Clinical Operations Roles

Location

Brazil

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

As an In-House CRA you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-119053

Expiry date

01/01/0001

Bruna Duarte

Author

Bruna Duarte
Read more Shortlist Save this role
IHCRA Argentina (Hybrid mode)

Salary

Location

Argentina, Buenos Aires

Department

Clinical Monitoring

Location

Buenos Aires

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

We are currently seeking an IHCRA to join our diverse and dynamic team. As an IHCRA at ICON, you will play a pivotal role in supporting the execution and management of clinical trials, contributing to

Reference

JR130229

Expiry date

01/01/0001

Florencia Pistolesi Read more Shortlist Save this role
Senior Clinical Trial Transparency Associate

Salary

Location

Poland

Department

Clinical Operations Roles

Location

Poland

Remote Working

Office Based

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

As a Senior Clinical Trial Transparency Associate you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence. You will oversee and

Reference

2025-118310

Expiry date

01/01/0001

Swathy Anandan Read more Shortlist Save this role
Clinical Study Administrator - Hamburg based

Salary

Location

Germany

Department

Clinical Operations Roles

Location

Germany

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

The Clinical Study Administrator (CSA) assists in the coordination and administration of the study activities from the start up to execution and close out, and within the Local Study Team (LST) to ens

Reference

2025-119101

Expiry date

01/01/0001

Roxana Rosca

Author

Roxana Rosca
Read more Shortlist Save this role
View Jobs

Browse popular job categories below or search all jobs above