Principal Scientist
About the role
This vacancy has now expired. Please click here to view live vacancies.
At ICON, it's our people that set us apart. Our diverse teams enable us to become a better partner to our customers and help us to fulfil our mission to advance and improve patients' lives. Our 'Own It' culture is driven by four key values that bring us together as individuals and set us apart as an organisation: Accountability & Delivery, Collaboration, Partnership and Integrity. We want to be the Clinical Research Organisation that delivers excellence to our clients and to patients at every touch-point. In short, to be the partner of choice in drug development. That's our vision. We're driven by it. And we need talented people who share it. If you're as driven as we are, join us. You'll be working in a dynamic and supportive environment, with some of the brightest and the friendliest people in the sector, and you'll be helping shape an industry.
- Recognize, exemplify and adhere to ICON's values which centers around our commitment to People, Clients and Performance.
- As a member of staff, the employee I expected to embrace and contribute to our culture of process improvement with a focus on streamlining our processes adding value to our business and meeting client needs.
- Travel (approximately 1%) domestic and/or international.
- Perform Bioanalytical method development and method validation for the quantification of NCE, NBE and Biomarkers in tissues and biological fluids. Key experience in ELISA, MSD (ECLA), ELLA, and Gyros Lab preferred.
- Prepare Bioanalytical method documents.
- May manage analytical studies and act as scientific consultant to clients, and internal scientific consultant within Icon.
- Prepare analysis plans suitable to the clients needs and obtain client approval of these.
- Work with analytical teams to ensure that study plans and validation plans, as appropriate are complied with.
- Identify changes to scope of work and notify contracts of need for change order.
- Review all data in accordance with direction documents and ensureresults are documented accurately, completely and compliant with GLP/GCP regulations and SOPs .
- Document all work and results accurately, completely and compliant with GXP regulations and SOP's.
- Generate high quality analytical results. Ensure smooth transfer of data to PI's and participate in evaluation and interpretation of data.
- Lead investigations of instrumental and procedural problems.
- Evaluate new equipment or technologies and make recommendations to management on utility for the laboratory and business.
- Approve release of method development and non-GXP data
- Check and verify laboratory notebooks and other analytical data as required.
- Author SOPs as needed. Maintain awareness of and adherence to all current SOPs.
- All other duties as needed.
Minimum Requirements: Bachelor degree with 6+ years, Masters with 4+ years, or PhD with 2+ years in a relevant field.
Benefits of Working in ICON: Our success depends on the quality of our people. That's why we've made it a priority to build a culture that rewards high performance and nurtures talent. We offer very competitive salary packages. And to keep them competitive, we regularly benchmark them against our competitors. Our annual bonuses reflect delivery of performance goals - both ours and yours. We also provide a range of health-related benefits to employees and their families and offer competitive retirement plans - and related benefits such as life assurance - so you can save and plan with confidence for the years ahead. But beyond the competitive salaries and comprehensive benefits, you'll benefit from an environment where you are encouraged to fulfil your sense of purpose and drive lasting change. ICON is an equal opportunity and inclusive employer and is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know through the form below.
Impactful work. Meaningful careers. Quality rewards.
At ICON, our employees are our greatest strength. That’s why we are committed to empowering you to live your best life, both inside and outside of work. Whether your ambition is lead a global team, become a deep scientific or technical expert, work in-house with our customers or gain experience in a variety of different ICON functions, we will support you in realising your full potential. See all locations Learn more about Our Culture at ICON
Day in the life
.png)
Teaser label
IndustryContent type
BlogsPublish date
07/07/2025
Summary
Precision at the Outset: The Strategic Role of Site Selection and Activation in Clinical Trials The success of any clinical trial begins well before the first patient is enrolled. Behind every sit
.png)
Teaser label
IndustryContent type
BlogsPublish date
07/04/2025
Summary
Cybersecurity in Clinical Data Management In clinical research, data is both a vital asset and a significant responsibility. As trials become increasingly digitised and decentralised, the protectio
.png)
Teaser label
IndustryContent type
BlogsPublish date
07/03/2025
Summary
Finding the Specialisation for You Clinical research is a dynamic, multidisciplinary field that brings together scientific innovation, operational rigour and patient-centric thinking. While many
Similar jobs at ICON
Salary
Location
Turkey
Department
Clinical Monitoring
Location
Turkey
Remote Working
Home-Based
Business Area
ICON Strategic Solutions
Job Categories
Clinical Monitoring
Job Type
Permanent
Description
As a CRA you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.
Reference
2025-119032
Expiry date
01/01/0001
Author
Tuba SuAuthor
Tuba SuSalary
Location
India, Bangalore
Location
Bangalore
Chennai
Bengaluru
Remote Working
Home or Office
Business Area
ICON Full Service & Corporate Support
Job Categories
Clinical Data Management
Job Type
Permanent
Description
We are currently seeking a Clinical Data Coordinator II to join our diverse and dynamic team. As a Clinical Data Coordinator II at ICON, you will play a pivotal role in designing and analyzing clinica
Reference
JR131289
Expiry date
01/01/0001
Author
Sunidhi SinhaAuthor
Sunidhi SinhaSalary
Location
India, Chennai
Location
Chennai
Trivandrum
Remote Working
Office Based
Business Area
ICON Full Service & Corporate Support
Job Categories
Clinical Programming
Job Type
Permanent
Description
We are currently seeking a Clinical Data Science Programmer to join our diverse and dynamic team. As a Clinical Data Programmer at ICON, you will play a pivotal role in designing and analyzing clinica
Reference
JR132103
Expiry date
01/01/0001
Author
Ekta Chandra SrivastavaAuthor
Ekta Chandra SrivastavaSalary
Location
India
Department
Biometrics Roles
Location
India
Remote Working
Home-Based
Business Area
ICON Strategic Solutions
Job Categories
Biometrics Portfolio
Job Type
Permanent
Description
As a Statistical Programmer you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.
Reference
2025-120666
Expiry date
01/01/0001
Author
Himangshu Skekhar DasAuthor
Himangshu Skekhar DasSalary
Location
Korea, South
Department
Clinical Monitoring
Location
South Korea
Seoul
Remote Working
Home-Based
Business Area
ICON Strategic Solutions
Job Categories
Clinical Monitoring
Job Type
Permanent
Description
(Sr.) CRA I or II, Home-based, South Korea As a (Sr.) CRA I or II you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.
Reference
2025-120101
Expiry date
01/01/0001
Author
Sonia OhAuthor
Sonia OhSalary
Location
France
Department
Clinical Monitoring
Location
France
Remote Working
Home-Based
Business Area
ICON Strategic Solutions
Job Categories
Clinical Monitoring
Job Type
Permanent
Description
ICON plc is a world-leading healthcare intelligence and clinical research organisation. From molecule to medicine, we advance clinical research providing outsourced services to pharmaceutical, biotech
Reference
2025-120220
Expiry date
01/01/0001
Author
Dominique CarilienAuthor
Dominique Carilien