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Senior Clinical Trial Manager

JR069470

About the role

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Clinical Trial Manager

Location: Home-based (anywhere in the US)

At ICON, it's our people that set us apart.

As a global provider of drug development solutions, our work is serious business. But that doesn't mean you can't have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry! Are you one of them?

At ICON, we have an incredible opportunity for an expert Clinical Trial Manager to join the team in the US.

The Role

The Senior Clinical Trial Manager (CTM) is responsible for the delivery of all clinical aspects of the study. The Senior CTM oversees the clinical portion of the budget, develops monitoring plans & tools, trains CRAs, drives enrolment and study start-up activities, reviews trip reports, implements corrective and preventative action plans, liaises with the Sponsor, vendors & cross-functional teams, identifies & mitigates risks that may impact clinical delivery, and provides reporting & metrics on all clinical activities. The Senior CTM will also participate in Sponsor, Investigator and bid defense meetings.

What you need

  • 4 year degree or equivalent combination of education & experience
  • 4 years of clinical research experience
  • Demonstrated ability to drive the clinical deliverables of a study
  • Subject matter expertise in the designated therapeutic area
  • Prior monitoring experience is preferred
  • Ability to travel up to 20%
  • Fluent in local language - both written & verbal

Why join us?

Other than working with an outstanding team of ambitious people, we also offer a very competitive benefits package. This varies from country to country so a dedicated recruiter will discuss this with you at interview stage.

We care about our people as they are the key to our success. We provide an open and friendly work environment where we empower people and provide them with opportunities to develop their long term career.

Ongoing development is vital to us, and as a Clinical Trial Manager, you will have the opportunity to progress your career, with the potential to move into other related areas to improve your skillset. Our benefits package is competitive, our scope is international and we sincerely care about our people and their success.

ICON is an equal opportunity employer and committed to providing a workplace free of any discrimination or harassment.

EOE race/color/religion/sex/sexual orientation/gender identity/disability/vet/national origin

List #1

Day in the life

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Central Monitoring vs On Site Monitoring

Teaser label

Industry

Content type

Blogs

Publish date

04/03/2026

Summary

Understanding Central Monitoring vs On Site Monitoring Monitoring is a core component of clinical trial oversight. It ensures that studies are conducted in line with the protocol, that data is re

Teaser label

Learn the difference between central monitoring and on site monitoring and how both support patient safety and data quality.

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Francis' Journey back to ICON

Teaser label

Our People

Content type

Blogs

Publish date

03/26/2026

Summary

Why Francis returned to ICON: building a long-term career in clinical research Francis Kayamba is a Clinical Research Associate based in Johannesburg, South Africa. He first joined ICON in February

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Francis Kayamba shares what drew him back to ICON and how the sponsor-embedded model works.

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Lydia's Journey Back to ICON

Teaser label

Our People

Content type

Blogs

Publish date

03/24/2026

Summary

Career paths are rarely straightforward, especially in the fast moving world of clinical research. For many professionals, gaining experience across organisations can provide valuable perspectiv

Teaser label

Learn about Lydia's return to ICON and why she felt it was a natural choice.

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