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Senior CRA - Home or Office Based

060739_1573726435

About the role

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Senior Clinical Research Associate (SCRA)
Location: Office based in Johannesburg or home based in South Africa
At ICON, it's our people that set us apart.
As a global provider of drug development solutions, our work is serious business. But that doesn't mean you can't have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry. Are you one of them?
As a Senior Clinical Research Associate at ICON, you'll work within a large-scale, fast-paced environment alongside a close-knit team of highly qualified CRAs to identify, select, initiate and close-out investigational sites for clinical studies in phases II - III, ensuring adherence to applicable regulations and principles of ICH-GCP. We pride ourselves on our amazing company culture, where we work as one team to achieve industry-leading results.
The role
  • Working independently and proactively to coordinate all necessary activities required to set up and monitor a study, completing accurate study status reports and maintaining study documentation
  • Submission of protocol, consent documents for ethics/IRB approval and assist in preparing regulatory submissions as requested
  • Participate in preparing and reviewing study documentation and feasibility studies for new proposals as required
  • Managing sponsor generated queries efficiently and responsible for study cost effectiveness
  • Dependent on level of experience you may assist in training and mentoring less experienced CRA's and/or manage CRA's working on international projects

What you need
  • 18 months+ of monitoring experience in phase I-III trials as a CRA
  • Availability to travel (plane or car) 60%
  • Knowledge of ICG GCP guidelines and expertise to review and evaluate medical data
  • Excellent communication and interpersonal skills, both written and verbal enabling you to deal with queries in a timely manner
  • Ability to produce accurate work to tight deadlines within a pressurized environment

Why join us?
Ongoing development is vital to us, and as a Senior CRA you will have the opportunity to progress your career, with the potential to move into other related areas to enhance your skill set. Our benefits package is competitive, our scope is international and we genuinely care about our people and their success.
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Day in the life

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Francis' Journey back to ICON

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Our People

Content type

Blogs

Publish date

03/26/2026

Summary

Why Francis returned to ICON: building a long-term career in clinical research Francis Kayamba is a Clinical Research Associate based in Johannesburg, South Africa. He first joined ICON in February

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Francis Kayamba shares what drew him back to ICON and how the sponsor-embedded model works.

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Lydia's Journey Back to ICON

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Content type

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Publish date

03/24/2026

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Career paths are rarely straightforward, especially in the fast moving world of clinical research. For many professionals, gaining experience across organisations can provide valuable perspectiv

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Learn about Lydia's return to ICON and why she felt it was a natural choice.

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Driving Trials Forward: Study Start-Up Leadership at ICON

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03/16/2026

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Driving Study Start-Up: James Pereira's Journey at ICON James Pereira's career in clinical research has been shaped by a single driving question: how do we get studies started faster? From his earl

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Explore James Pereira's career in study start-up at ICON, leading global teams to accelerate patient access.

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