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Senior CRA - Home or Office Based

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About the role

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Senior Clinical Research Associate (SCRA)
Location: Office based in Johannesburg or home based in South Africa
At ICON, it's our people that set us apart.
As a global provider of drug development solutions, our work is serious business. But that doesn't mean you can't have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry. Are you one of them?
As a Senior Clinical Research Associate at ICON, you'll work within a large-scale, fast-paced environment alongside a close-knit team of highly qualified CRAs to identify, select, initiate and close-out investigational sites for clinical studies in phases II - III, ensuring adherence to applicable regulations and principles of ICH-GCP. We pride ourselves on our amazing company culture, where we work as one team to achieve industry-leading results.
The role
  • Working independently and proactively to coordinate all necessary activities required to set up and monitor a study, completing accurate study status reports and maintaining study documentation
  • Submission of protocol, consent documents for ethics/IRB approval and assist in preparing regulatory submissions as requested
  • Participate in preparing and reviewing study documentation and feasibility studies for new proposals as required
  • Managing sponsor generated queries efficiently and responsible for study cost effectiveness
  • Dependent on level of experience you may assist in training and mentoring less experienced CRA's and/or manage CRA's working on international projects

What you need
  • 18 months+ of monitoring experience in phase I-III trials as a CRA
  • Availability to travel (plane or car) 60%
  • Knowledge of ICG GCP guidelines and expertise to review and evaluate medical data
  • Excellent communication and interpersonal skills, both written and verbal enabling you to deal with queries in a timely manner
  • Ability to produce accurate work to tight deadlines within a pressurized environment

Why join us?
Ongoing development is vital to us, and as a Senior CRA you will have the opportunity to progress your career, with the potential to move into other related areas to enhance your skill set. Our benefits package is competitive, our scope is international and we genuinely care about our people and their success.
List #1

Day in the life

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Leading Through Change: Zhong Yao's Journey at ICON in China

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Our People

Content type

Blogs

Publish date

12/10/2025

Summary

Zhong Yao's Journey at ICON Plc in China Zhong Yao's career in clinical research spans over two decades, with leadership roles across major CROs and a commitment to advancing healthcare in China.

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From culture to collaboration, Zhong Yao explains how ICON China delivers quality clinical trials, and empowers local talent.

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How Data Moves Through a Clinical Trial

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Industry

Content type

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Publish date

12/01/2025

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How Data Moves Through a Clinical Trial Clinical research depends on one essential element: trustworthy data. Every safety decision, every statistical conclusion and every regulatory submission i

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Discover how data flows through a clinical trial and learn where your skills could fit within clinical research.

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Quality and Compliance - A Plain Language Guide

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Industry

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11/28/2025

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Quality and Compliance for New Entrants:           A Plain Language Guide Quality and compliance can feel like dense subjects when you are entering clinical research for the first time. Many job

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A clear, practical introduction to quality and compliance for those starting a career in clinical research.

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