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Senior Clinical Research Associate (SCRA)

Location: Johannesburg

At ICON, it’s our people that set us apart.

As a global provider of drug development solutions, our work is serious business. But that doesn’t mean you can’t have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry. Are you one of them?

As a Senior Clinical Research Associate at ICON, you’ll work within a large-scale, fast-paced environment alongside a close-knit team of highly qualified CRAs to identify, select, initiate and close-out investigational sites for clinical studies in phases II – III, ensuring adherence to applicable regulations and principles of ICH-GCP. We pride ourselves on our amazing company culture, where we work as one team to achieve industry-leading results.

The role

Working independently and proactively to coordinate all necessary activities required to set up and monitor a study, completing accurate study status reports and maintaining study documentation
Submission of protocol, consent documents for ethics/IRB approval and assist in preparing regulatory submissions as requested
Participate in preparing and reviewing study documentation and feasibility studies for new proposals as required
Managing sponsor generated queries efficiently and responsible for study cost effectiveness
Dependent on level of experience you may assist in training and mentoring less experienced CRA’s and/or manage CRA’s working on international projects

What you need

18 months+ of monitoring experience in phase I-III trials as a CRA
Availability to travel (plane or car) 60%
Knowledge of ICG GCP guidelines and expertise to review and evaluate medical data
Excellent communication and interpersonal skills, both written and verbal enabling you to deal with queries in a timely manner
Ability to produce accurate work to tight deadlines within a pressurized environment

Why join us?

Ongoing development is vital to us, and as a Senior CRA you will have the opportunity to progress your career, with the potential to move into other related areas to enhance your skill set. Our benefits package is competitive, our scope is international and we genuinely care about our people and their success.

ICON is an equal opportunity employer and committed to providing a workplace free of any discrimination or harassment.

EOE race/color/religion/sex/sexual orientation/gender identity/disability/vet/national origin

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Impactful work. Meaningful careers. Quality rewards.

At ICON, our employees are our greatest strength. That’s why we are committed to empowering you to live your best life, both inside and outside of work. Whether your ambition is lead a global team, become a deep scientific or technical expert, work in-house with our customers or gain experience in a variety of different ICON functions, we will support you in realising your full potential.
Learn more about Our Culture at ICON

List #1

Day in the life

Driving Trials Forward: Study Start-Up Leadership at ICON

Teaser label

Our People

Content type

Blogs

Publish date

03/16/2026

Summary

Driving Study Start-Up: James Pereira's Journey at ICON James Pereira's career in clinical research has been shaped by a single driving question: how do we get studies started faster? From his earl

Teaser label

Explore James Pereira's career in study start-up at ICON, leading global teams to accelerate patient access.

Who’s Who in a Clinical Trial Team

Teaser label

Inside ICON

Content type

Blogs

Publish date

03/15/2026

Summary

Who's Who In a Clinical Trial Team Clinical trials rely on large, cross functional teams working together across countries, time zones and specialisms. For those new to the industry, the number of

Teaser label

Understand the key roles in a clinical trial team, from study start up and site activation to data, safety and quality.

Understanding Roles in a Clinical Trial: Sponsors, CROs, and Sites

Teaser label

Industry

Content type

Blogs

Publish date

02/16/2026

Summary

What Sponsors, CROs, and Sites Each Do Clinical research brings together many organisations, each with a specific role in delivering a clinical trial. For those new to the industry, the relationsh

Teaser label

Learn how clinical trials are delivered by understanding the roles of sponsors, CROs, and sites.

View all

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Senior CRA

About the role

This vacancy has now expired. Please click here to view live vacancies.

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