JUMP TO CONTENT
Shortlist
search jobs Search

Our Culture Application Process Career Resources Our Mission & Values

Senior CRA

059904_2

About the role

This vacancy has now expired. Please click here to view live vacancies.
Senior Clinical Research Associate (SCRA)
Location: Johannesburg
 
At ICON, it’s our people that set us apart.
 
As a global provider of drug development solutions, our work is serious business. But that doesn’t mean you can’t have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry. Are you one of them?
 
As a Senior Clinical Research Associate at ICON, you’ll work within a large-scale, fast-paced environment alongside a close-knit team of highly qualified CRAs to identify, select, initiate and close-out investigational sites for clinical studies in phases II – III, ensuring adherence to applicable regulations and principles of ICH-GCP. We pride ourselves on our amazing company culture, where we work as one team to achieve industry-leading results.
 
The role
  • Working independently and proactively to coordinate all necessary activities required to set up and monitor a study, completing accurate study status reports and maintaining study documentation
  • Submission of protocol, consent documents for ethics/IRB approval and assist in preparing regulatory submissions as requested
  • Participate in preparing and reviewing study documentation and feasibility studies for new proposals as required
  • Managing sponsor generated queries efficiently and responsible for study cost effectiveness
  • Dependent on level of experience you may assist in training and mentoring less experienced CRA’s and/or manage CRA’s working on international projects 
What you need
  • 18 months+ of monitoring experience in phase I-III trials as a CRA
  • Availability to travel (plane or car) 60%
  • Knowledge of ICG GCP guidelines and expertise to review and evaluate medical data
  • Excellent communication and interpersonal skills, both written and verbal enabling you to deal with queries in a timely manner
  • Ability to produce accurate work to tight deadlines within a pressurized environment
Why join us?
Ongoing development is vital to us, and as a Senior CRA you will have the opportunity to progress your career, with the potential to move into other related areas to enhance your skill set. Our benefits package is competitive, our scope is international and we genuinely care about our people and their success.
ICON is an equal opportunity employer and committed to providing a workplace free of any discrimination or harassment.
EOE race/color/religion/sex/sexual orientation/gender identity/disability/vet/national origin
 
 
Insert Approved Brand Image from the URL Lists at the bottom of the Job Advert  into Taleo – Taleo will require the URL in order to attach image.  Here is an example of an image:
 
 
 
List #1

Day in the life

Heartbeat vitals on monitor
Central Monitoring vs On Site Monitoring

Teaser label

Industry

Content type

Blogs

Publish date

04/03/2026

Summary

Understanding Central Monitoring vs On Site Monitoring Monitoring is a core component of clinical trial oversight. It ensures that studies are conducted in line with the protocol, that data is re

Teaser label

Learn the difference between central monitoring and on site monitoring and how both support patient safety and data quality.

Read more
middle aged male wearing shirt
Francis' Journey back to ICON

Teaser label

Our People

Content type

Blogs

Publish date

03/26/2026

Summary

Why Francis returned to ICON: building a long-term career in clinical research Francis Kayamba is a Clinical Research Associate based in Johannesburg, South Africa. He first joined ICON in February

Teaser label

Francis Kayamba shares what drew him back to ICON and how the sponsor-embedded model works.

Read more
Lydia's Journey Back to ICON

Teaser label

Our People

Content type

Blogs

Publish date

03/24/2026

Summary

Career paths are rarely straightforward, especially in the fast moving world of clinical research. For many professionals, gaining experience across organisations can provide valuable perspectiv

Teaser label

Learn about Lydia's return to ICON and why she felt it was a natural choice.

Read more
View all

Similar jobs at ICON

Site Contracts Negotiator II

Salary

Location

Mexico, Mexico City

Location

Mexico City

Remote Working

Remote or Office

Business Area

ICON Full Service & Corporate Support

Job Categories

Contracts Administration

Job Type

Permanent

Description

We are currently seeking a Site Contracts Negotiator II to join our diverse and dynamic team. As a Site Contracts Negotiator II at ICON, you will independently manage the negotiation and execution of

Reference

JR137461

Expiry date

01/01/0001

Olivia Molina

Author

Olivia Molina
Olivia Molina

Author

Olivia Molina
Read more Shortlist Save this role
Read more Shortlist Save this role
Clinical Research Associate - All levels

Salary

Location

Brazil, Sao Paulo

Location

Sao Paulo

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

We are currently seeking a Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate II at ICON, you will play a pivotal role in designing and analyzing cli

Reference

JR138161

Expiry date

01/01/0001

Bruna Duarte

Author

Bruna Duarte
Bruna Duarte

Author

Bruna Duarte
Read more Shortlist Save this role
Read more Shortlist Save this role
Pharmacovigilance Associate

Salary

Location

Brazil, Sao Paulo

Location

Sao Paulo

Mexico City

Remote Working

Remote or Office

Business Area

ICON Full Service & Corporate Support

Job Categories

Drug Safety

Job Type

Permanent

Description

We are currently seeking a Pharmacovigilance Associate to join our diverse and dynamic team. As a Pharmacovigilance Associate at ICON, you will play a vital role in monitoring and ensuring the safety

Reference

JR148124

Expiry date

01/01/0001

Florencia Pistolesi

Author

Florencia Pistolesi
Florencia Pistolesi

Author

Florencia Pistolesi
Read more Shortlist Save this role
Read more Shortlist Save this role
CRA I

Salary

Location

Argentina, Buenos Aires

Location

Buenos Aires

Remote Working

Remote or Office

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

We are currently seeking a Clinical Research Associate to join our diverse and dynamic team at ICON Plc. As a key member of our research department, you will be responsible for overseeing and coordina

Reference

JR145113

Expiry date

01/01/0001

Florencia Pistolesi

Author

Florencia Pistolesi
Florencia Pistolesi

Author

Florencia Pistolesi
Read more Shortlist Save this role
Read more Shortlist Save this role
Site Specialist II

Salary

Location

Mexico, Mexico City

Location

Mexico City

Remote Working

Hybrid

Business Area

ICON Full Service & Corporate Support

Job Categories

Study Start Up

Job Type

Permanent

Description

Job Description Summary:Support preparation, process and tracking of regulatory and site level critical documents and of site activation tasks required for study site activation in accordance with ICO

Reference

JR140536

Expiry date

01/01/0001

Florencia Pistolesi

Author

Florencia Pistolesi
Florencia Pistolesi

Author

Florencia Pistolesi
Read more Shortlist Save this role
Read more Shortlist Save this role
Senior CRA

Salary

Location

US, Downers Grove, IL

Location

Downers Grove

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

We are currently seeking a Senior Clinical Research Associate (CRA) to join our diverse and dynamic team. As a Senior CRA at ICON Plc, you will play a critical role in overseeing and managing clinical

Reference

JR145071

Expiry date

01/01/0001

Melissa Benner

Author

Melissa Benner
Melissa Benner

Author

Melissa Benner
Read more Shortlist Save this role
Read more Shortlist Save this role
View Jobs

Browse popular job categories below or search all jobs above