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Senior CRA

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About the role

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Senior Clinical Research Associate (SCRA)
Location: Johannesburg
 
At ICON, it’s our people that set us apart.
 
As a global provider of drug development solutions, our work is serious business. But that doesn’t mean you can’t have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry. Are you one of them?
 
As a Senior Clinical Research Associate at ICON, you’ll work within a large-scale, fast-paced environment alongside a close-knit team of highly qualified CRAs to identify, select, initiate and close-out investigational sites for clinical studies in phases II – III, ensuring adherence to applicable regulations and principles of ICH-GCP. We pride ourselves on our amazing company culture, where we work as one team to achieve industry-leading results.
 
The role
  • Working independently and proactively to coordinate all necessary activities required to set up and monitor a study, completing accurate study status reports and maintaining study documentation
  • Submission of protocol, consent documents for ethics/IRB approval and assist in preparing regulatory submissions as requested
  • Participate in preparing and reviewing study documentation and feasibility studies for new proposals as required
  • Managing sponsor generated queries efficiently and responsible for study cost effectiveness
  • Dependent on level of experience you may assist in training and mentoring less experienced CRA’s and/or manage CRA’s working on international projects 
What you need
  • 18 months+ of monitoring experience in phase I-III trials as a CRA
  • Availability to travel (plane or car) 60%
  • Knowledge of ICG GCP guidelines and expertise to review and evaluate medical data
  • Excellent communication and interpersonal skills, both written and verbal enabling you to deal with queries in a timely manner
  • Ability to produce accurate work to tight deadlines within a pressurized environment
Why join us?
Ongoing development is vital to us, and as a Senior CRA you will have the opportunity to progress your career, with the potential to move into other related areas to enhance your skill set. Our benefits package is competitive, our scope is international and we genuinely care about our people and their success.
ICON is an equal opportunity employer and committed to providing a workplace free of any discrimination or harassment.
EOE race/color/religion/sex/sexual orientation/gender identity/disability/vet/national origin
 
 
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List #1

Day in the life

Two medics at ICON clinical research clinic
The Strategic Role of Site Selection and Activation in Clinical Trials

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Publish date

10/28/2025

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Precision at the Outset: The Strategic Role of Site Selection and Activation in Clinical Trials The success of any clinical trial begins well before the first patient is enrolled. Behind every sit

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Explore the critical role of site selection and activation in clinical trials.

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A Career Focused on Patients: Daniela's Journey at ICON

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Our People

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Publish date

10/27/2025

Summary

Daniela’s Journey at ICON Daniela Gutierrez’s career at ICON has been a journey of transition, determination, and purpose. What began as a role in study start-up has evolved into a position deeply

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Daniela shares insights into how collaboration, purpose, and innovation drive every part of her work.

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ICON Careers Spotlight: Chris Maguire, Director of Finance Business Partnering

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10/15/2025

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Chris Maguire’s Journey at ICON Over the past eight years at ICON, Chris Maguire has held six roles within the finance function, each expanding his expertise and sharpening his ability to support

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Discover how Chris Maguire’s collaborative approach has shaped a rewarding career journey at ICON.

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