Site Management Associate I

MEXICO CITY. OFFICE BASED.

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

As a SMA II at ICON, you will support the management and monitor of clinical trial sites by ensuring compliance with study protocols, regulatory requirements, and Good Clinical Practice (GCP) guidelines.

What You Will Do

You will contribute to clinical research activities, taking ownership of key CTA deliverables while collaborating closely with cross-functional teams.

Key responsibilities include:

• Providing advanced administrative and operational support to clinical trial teams across study start-up, maintenance, and close-out activities.

• This is a non site-facing role. The position focuses on clinical trial administrative and operational support and does not involve direct on-site monitoring or routine in-person interaction with clinical sites.

• Managing and maintaining Trial Master File (TMF) documentation, ensuring completeness, accuracy, and inspection readiness in compliance with GCP and regulatory requirements.

• Supporting site activation activities, including collection, review, and tracking of essential regulatory documents.

• Acting as a key point of contact for internal stakeholders, sites, and vendors to ensure effective communication and coordination throughout the study lifecycle.

• Tracking study progress, site metrics, and deliverables, proactively identifying risks or delays and supporting resolution.

• Coordinating study-related logistics such as investigator payments, supplies, and document workflows.

• Assisting with audit and inspection readiness activities, ensuring documentation is complete and compliant.

• Supporting contract and budget tracking activities in collaboration with relevant teams.

• Mentoring or providing guidance to junior CTAs or administrative staff, as applicable.

Your Profile

You will bring solid clinical research experience with a strong focus on clinical trial administration, along with the following qualifications and skills.

Required qualifications and experience:

• Bachelor’s degree in life sciences, healthcare administration, clinical research, or a related field.

• 2+ years of experience in clinical research, with strong exposure to CTA responsibilities and TMF management.

• Solid understanding of clinical trial processes, including study start-up, regulatory documentation, and site support activities.

• Strong knowledge of GCP guidelines and applicable regulatory requirements.

• Excellent organizational and time management skills, with the ability to manage multiple priorities in a fast-paced environment.

• High attention to detail and strong documentation skills.

• Strong communication and interpersonal skills, with the ability to collaborate effectively with cross-functional teams and external stakeholders.

• Proactive mindset with strong problem-solving and risk identification capabilities.

• Experience with clinical systems (e.g., eTMF, CTMS) and Microsoft Office tools is preferred.

Work Model

• This role is office-based

What ICON can offer you:
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply