Senior Clinical Pharmacologist

Senior Clinical Pharmacologist

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

Senior Clinical Pharmacologist - Fixed Term min - 12 months

(Director, Clinical Pharmacology)

We are currently seeking a Director, Clinical Pharmacology to join our diverse and dynamic team. As a Director, Clinical Pharmacology at ICON, you will play a pivotal role in leading the design, execution, and interpretation of clinical pharmacology studies to support the development of innovative therapies. You will ensure the strategic integration of pharmacokinetic and pharmacodynamic data into clinical trial designs, driving informed decision-making and advancing therapeutic development.

What You Will Be Doing:

-Developing and executing development strategy in supporting the selection of the right dose-regimen, in the right population, using the relevant biomarkers and the right endpoint to achieve differentiation and develop a CP package that enables global product registration.
- Design and execution of appropriate modeling plans along with the Pharmacometrician assigned to the project.
-Contribute to the design and planning of pre-clinical studies to inform translational modeling.
-Contribute to the design and dose selection of the FIH study (SAD,MAD).
-Contribute to the required components of regulatory submissions and be responsible for responding to regulatory authority queries.
- Will drive early alignment on key development questions where CP principles could be applied.
-Actively participate in project discussions with project teams to understand the scope and need for QCP² involvement and develop appropriate plans that address the key development questions.
-Attend governance meetings, as necessary, ensure that CP plans are flawlessly executed, on time for efficient decision making.
-Keep up-to-date knowledge of model-based drug development with focus on Clinical pharmacology, biopharmaceutics, PKPD & other related analytical sciences including implementation of innovative methods to preclinical research, translational sciences and clinical development.
-Devising and implementing strategy for ensuring an integrated approach for the utilization of expertise through close partnership with preclinical, clinical, and regulatory.
-Coordination of clinical pharmacology related outsourced activities.
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Your Profile:

· A PhD in Biological Sciences, Bioengineering or a related field with at least 13 years of experience in pharmaceutical or related fields.
- Fluent in written and spoken English 
- Good written and oral communication skills
-Knowledge and understanding of innovative approaches in clinical pharmacokinetics, clinical pharmacology, PK and PK-PD modeling approaches and their applications in model based drug development
-A thorough knowledge of the clinical development process
-Ability to drive alignment around his/her vision and strategy across departments 

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What ICON can offer you:
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply