Sr. Clinical Trial Manager - CNS/Rare Diseases (Home-based)
About the role
This vacancy has now expired. Please click here to view live vacancies.
As a global provider of drug development solutions, our work is serious business. But that doesn't mean you can't have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry! Are you one of them?
At ICON, we have an incredible opportunity for an expert Sr. Clinical Trial Manager to join the team in the US.
The Role:
The Sr. Clinical Trial Manager is responsible for the delivery of all clinical aspects of the study. The CTM oversees the clinical portion of the budget, develops monitoring plans & tools, trains CRAs, drives enrolment and study start-up activities, reviews trip reports, implements corrective and preventative action plans, liaises with the Sponsor, vendors & cross-functional teams, identifies & mitigates risks that may impact clinical delivery, and provides reporting & metrics on all clinical activities. The CTM will also participate in Sponsor, Investigator and bid defense meetings.
What you need:
- 4 year degree or equivalent combination of education & experience
- Demonstrated ability to drive the clinical deliverables of a study
- Subject matter expertise in CNS and/or Rare Diseases
- Prior monitoring experience is preferred
- Ability to travel up to 20%
- Fluent in local language - both written & verbal
Why join us?
Other than working with an outstanding team of ambitious people, we also offer a very competitive benefits package. This varies from country to country so a dedicated recruiter will discuss this with you at interview stage.
We care about our people as they are the key to our success. We provide an open and friendly work environment where we empower people and provide them with opportunities to develop their long term career.
Ongoing development is vital to us, and as a Clinical Trial Manager, you will have the opportunity to progress your career, with the potential to move into other related areas to improve your skillset. Our benefits package is competitive, our scope is international and we sincerely care about our people and their success.
ICON is an equal opportunity employer and committed to providing a workplace free of any discrimination or harassment.
EOE race/color/religion/sex/sexual orientation/gender identity/disability/vet/national origin
Impactful work. Meaningful careers. Quality rewards.
At ICON, our employees are our greatest strength. That’s why we are committed to empowering you to live your best life, both inside and outside of work. Whether your ambition is lead a global team, become a deep scientific or technical expert, work in-house with our customers or gain experience in a variety of different ICON functions, we will support you in realising your full potential. Learn more about Our Culture at ICON
Day in the life
Teaser label
Our PeopleContent type
BlogsPublish date
02/05/2026
Summary
Building expertise through diverse roles and continuous learning Sinéad McKeon's career at ICON demonstrates how scientific training can evolve into strategic leadership. Now a Senior Manager in Lab
Teaser label
Our PeopleContent type
BlogsPublish date
02/05/2026
Summary
Shaping the Future of Patient Safety At ICON, patient safety is the foundation of everything we do. Hassan Aljobori, Director of Pharmacovigilance, shares his journey through nine years of growth
Teaser label
Our PeopleContent type
BlogsPublish date
01/26/2026
Summary
Sometimes the best way to recognise what you have is to experience life without it. For Izabella Grimaldi, a Clinical Research Associate II based in Brazil, that realisation came after seven months wo
Similar jobs at ICON
Salary
Location
Poland, Warsaw
Department
Clinical Monitoring
Location
Warsaw
Remote Working
Office Based
Business Area
ICON Full Service & Corporate Support
Job Categories
Clinical Monitoring
Job Type
Permanent
Description
Clinical Site Associate (CSA) We are currently seeking a Clinical Site Associate (CSA) to join our diverse and dynamic team. As an CSA at ICON, you will play a pivotal role in supporting clinical tria
Reference
JR141951
Expiry date
01/01/0001
Author
Tereza SvobodovaAuthor
Tereza SvobodovaSalary
Location
Spain, Madrid
Location
Madrid
Remote Working
Remote
Business Area
ICON Strategic Solutions
Job Categories
Clinical Monitoring
Job Type
Permanent
Description
We are currently seeking a Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate II at ICON, you will play a pivotal role in designing and analyzing cli
Reference
JR142939
Expiry date
01/01/0001
Author
Lola PomboAuthor
Lola PomboSalary
Location
Italy, Milan
Location
Milan
Remote Working
Office or Home
Business Area
ICON Strategic Solutions
Job Categories
Corporate Support
Job Type
Permanent
Description
We are currently seeking a Senior Contract Analyst to join our diverse and dynamic team. As a Senior Contract Analyst at ICON, you will play a pivotal role in managing contractual agreements, ensuring
Reference
JR141864
Expiry date
01/01/0001
Author
Vera StellinoAuthor
Vera StellinoSalary
Location
Czech Republic, Prague
Location
Prague
Remote Working
Remote
Business Area
ICON Strategic Solutions
Job Categories
Clinical Trial Support
Job Type
Permanent
Description
We are currently seeking a Clinical Trial Administrator to join our diverse and dynamic team. As a Clinical Trial Administrator at ICON, you will play a pivotal role in assisting with the design and a
Reference
JR143735
Expiry date
01/01/0001
Author
Jaroslav PolákAuthor
Jaroslav PolákSalary
Location
Netherlands, Utrecht, Zen
Location
Utrecht
Remote Working
Remote
Business Area
ICON Strategic Solutions
Job Categories
Clinical Monitoring
Job Type
Permanent
Description
We are currently seeking a Senior Clinical Research Associate (CRA) to join our diverse and dynamic team in the Netherlands. As a Senior CRA at ICON Plc, you will play a critical role in overseeing an
Reference
JR142945
Expiry date
01/01/0001
Author
Iris BrouwerAuthor
Iris BrouwerSalary
Location
India, Chennai
Department
Clinical Trial Management
Location
Chennai
Remote Working
Office Based
Business Area
ICON Full Service & Corporate Support
Job Categories
Regulatory Document Management
Job Type
Permanent
Description
We are currently seeking a Senior TMF Specialist to join our diverse and dynamic team. As a Senior TMF Specialist at ICON, you will play a pivotal role in managing the Trial Master File (TMF) for clin
Reference
JR142071
Expiry date
01/01/0001
Author
Amrutha SaidalaAuthor
Amrutha Saidala