JUMP TO CONTENT

Sr. Clinical Trial Manager - CNS/Rare Diseases (Home-based)

JR067030

About the role

This vacancy has now expired. Please click here to view live vacancies.

At ICON, it's our people that set us apart.

As a global provider of drug development solutions, our work is serious business. But that doesn't mean you can't have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry! Are you one of them?

At ICON, we have an incredible opportunity for an expert Sr. Clinical Trial Manager to join the team in the US.

The Role:

The Sr. Clinical Trial Manager is responsible for the delivery of all clinical aspects of the study. The CTM oversees the clinical portion of the budget, develops monitoring plans & tools, trains CRAs, drives enrolment and study start-up activities, reviews trip reports, implements corrective and preventative action plans, liaises with the Sponsor, vendors & cross-functional teams, identifies & mitigates risks that may impact clinical delivery, and provides reporting & metrics on all clinical activities. The CTM will also participate in Sponsor, Investigator and bid defense meetings.

What you need:

  • 4 year degree or equivalent combination of education & experience
  • Demonstrated ability to drive the clinical deliverables of a study
  • Subject matter expertise in CNS and/or Rare Diseases
  • Prior monitoring experience is preferred
  • Ability to travel up to 20%
  • Fluent in local language - both written & verbal

Why join us?

Other than working with an outstanding team of ambitious people, we also offer a very competitive benefits package. This varies from country to country so a dedicated recruiter will discuss this with you at interview stage.

We care about our people as they are the key to our success. We provide an open and friendly work environment where we empower people and provide them with opportunities to develop their long term career.

Ongoing development is vital to us, and as a Clinical Trial Manager, you will have the opportunity to progress your career, with the potential to move into other related areas to improve your skillset. Our benefits package is competitive, our scope is international and we sincerely care about our people and their success.

ICON is an equal opportunity employer and committed to providing a workplace free of any discrimination or harassment.

EOE race/color/religion/sex/sexual orientation/gender identity/disability/vet/national origin

List #1

Day in the life

Headshot of male
From Supporting Studies to Leading Teams: Yordan's Clinical Research Journey

Teaser label

Our People

Content type

Blogs

Publish date

06/10/2026

Summary

Why I Still Recommend the CTA Role After More Than 10 Years in Clinical Research Clinical Operations Manager Yordan Zahariev reflects on career growth, leadership and the opportunities a CTA role

Teaser label

Discover Yordan's career journey at ICON and learn how a CTA role can open doors across clinical research.

Read more
Building Careers Across Latin America

Teaser label

Our People

Content type

Blogs

Publish date

06/04/2026

Summary

After more than 20 years at ICON, Carolina Boari has witnessed the organisation's growth across Latin America while building a successful career of her own. Today, as Executive Director of Clini

Teaser label

Hear from Carolina about her career journey at ICON.

Read more
Headshot of female
Sajna's Biometrics Career Journey

Teaser label

Our People

Content type

Blogs

Publish date

05/26/2026

Summary

From Data Management to Leadership For Sajna Basant, a career in Biometrics has always been about more than data. “Data is not just numbers,” she explains. “It represents real people, their health

Teaser label

Discover how Sajna built her career in Biometrics at ICON.

Read more
View all

Similar jobs at ICON

CRA I

Salary

Location

France, Paris

Location

Paris

Remote Working

Hybrid

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

Clinical Research Associate I (CRA I) — Sponsor-dedicated, ParisAs a CRA I at ICON, you will join a team dedicated to a single global pharmaceutical sponsor, based in Paris. Working across Phase I to

Reference

JR154532

Expiry date

01/01/0001

Sophie Clarke

Author

Sophie Clarke
Read more Shortlist Save this role
Clinical Trial Associate

Salary

Location

Turkey, Istanbul

Location

Istanbul

Remote Working

Remote

Business Area

ICON Strategic Solutions (FSP)

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

As a Clinical Trial Associate at ICON, you will assist with the design and analysis of clinical trials, interpreting complex medical data, and contribute to the advancement of innovative treatments an

Reference

JR154793

Expiry date

01/01/0001

Tuba Su

Author

Tuba Su
Tuba Su

Author

Tuba Su
Read more Shortlist Save this role
Clinical Research Associate II

Salary

Location

China, Wuhan

Location

Wuhan

Remote Working

Remote or Office

Business Area

ICON Strategic Solutions (FSP)

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a CRA II at ICON, you will design and analyse clinical trials, interpreting complex medical data, and contribute to the advancement of innovative treatments and therapies.What You Will Do:You will

Reference

JR154352

Expiry date

01/01/0001

Irena Guo

Author

Irena Guo
Irena Guo

Author

Irena Guo
Read more Shortlist Save this role
Clinical Research Associate II

Salary

Location

China, Guangzhou

Location

Guangzhou

Remote Working

Remote or Office

Business Area

ICON Strategic Solutions (FSP)

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a CRA II at ICON, you will design and analyse clinical trials, interpreting complex medical data, and contribute to the advancement of innovative treatments and therapies.What You Will Do:You will

Reference

JR153545

Expiry date

01/01/0001

Irena Guo

Author

Irena Guo
Irena Guo

Author

Irena Guo
Read more Shortlist Save this role
Project Associate

Salary

Location

India, Bangalore

Location

Bangalore

Bengaluru

Remote Working

Hybrid

Business Area

ICON Strategic Solutions (FSP)

Job Categories

Project/ Program Management

Job Type

Permanent

Description

As a Project Associate at ICON, you will provide key administrative support in clinical operations and project management, ensuring projects align with contract and client expectations. What You Will

Reference

JR155167

Expiry date

01/01/0001

Makarandha Nargund Read more Shortlist Save this role
Senior Study Start Up Associate- Regulatory Affairs

Salary

Location

Korea, Seoul

Location

Seoul

Remote Working

Remote

Business Area

ICON Strategic Solutions (FSP)

Job Categories

Study Start Up

Job Type

Permanent

Description

As a Senior Study Start Up Associate at ICON, you will be working within a large-scale, fast-paced environment, supporting the Study Start Up Team Lead in developing and execute the plan for country a

Reference

JR155158

Expiry date

01/01/0001

Sonia Oh

Author

Sonia Oh
Sonia Oh

Author

Sonia Oh
Read more Shortlist Save this role
View Jobs

Browse popular job categories below or search all jobs above