JUMP TO CONTENT
Shortlist
search jobs Search
About the role ICON and you Application Process Day in the life Who we are

Principal Statistician - Europe home based or office based

JR062558

About the role

This vacancy has now expired. Please click here to view live vacancies.
Principal Biostatistician
ICON is a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries. We specialize in the strategic development, management and analysis of programs that support Clinical Development - from compound selection to Phase I-IV clinical studies.
Position Summary
This position will be accountable for the leadership of the Biostatistics and Programming activities of a program of studies of moderate complexity and/or of high value with high impact for the organization. Also responsible for planning, monitoring, organizing and reviewing activities of biostatisticians and programmers working on the assigned program of studies, ensuring individual studies and the overall program of studies and integrated analyses are delivered on time, on budget to required quality. Accountabilities also include maintenance of consistency across studies. Role could be based at our North Wales office or Home based.
Responsibilities:
  • Accountable for leading Biostatistics and Programming activities for a program of studies of high complexity and/or of high value with high impact.
  • Bio statistical input into the design of the program, Protocol input such as study design, sample size calculations and patient randomization schemes and Statistical aspects of case report form design
  • Review project database structures, edit checks and data management coding conventions
  • Preparation of statistical analysis plans including the definition of derived data, and the design of statistical tables, figures, and data listings for clinical summary reports
  • Statistical analysis, Interpretation of data and reporting of results.
  • Writing of the statistical methods sections of integrated study reports. Reviews draft integrated study reports.
  • Supports responses to regulatory questions on the design of the program, and any labelling claims following submission
  • Participates in presentations at client and investigator meetings.
  • Preparation of biostatistics input to ICON research proposals, and participates in proposal defense meetings and makes presentations at marketing meetings with prospective client.
  • Ongoing coaching and mentorship of team members.

Key Requirements:
  • M.S. degree in statistics, biostatistics, with relevant experience in the pharmaceutical industry or Ph.D. in statistics, biostatistics
  • Experience with oncology is required
  • In-depth knowledge of study designs, and statistical analysis applications in one or more therapeutic areas.
  • Excellent verbal and written communication skills as well as interpersonal and project management skills
  • Excellent knowledge of a wide variety of principles, theories and concepts in statistics and experimental design; must be able to apply them to the development and analysis of clinical trials
  • Excellent knowledge of clinical trials methodology, regulatory requirements, statistics and statistical software packages, including SAS are a must.
  • Experience leading a regulatory submission
  • Must be able to translate clients' needs into statistical practice and educate clients in the use of statistics.
List #1

Day in the life

Female portrait
A Career in Patient Safety: Karina's Journey at ICON

Teaser label

Our People

Content type

Blogs

Publish date

11/14/2025

Summary

Karina Espinoza's Journey at ICON Karina Espinoza's career in pharmacovigilance didn't begin with a grand plan. It started with a practical problem during her final year of a PhD in epidemiology, a

Teaser label

Explore a pharmacovigilance career at ICON through Karina Espinoza's story.

Read more
Headshot of female
How Patient Impact Shapes Clinical Operations

Teaser label

Our People

Content type

Blogs

Publish date

11/13/2025

Summary

A Career Built on Patient Impact: Victoria DeVeaugh Geiss's Journey at ICON Victoria DeVeaugh Geiss has spent more than two decades in clinical research, and one thing has stayed constant throughout

Teaser label

Victoria DeVeaugh Geiss shares insights from 20+ years in the industry and why patients remain at the heart of her work.

Read more
Two medics at ICON clinical research clinic
The Strategic Role of Site Selection and Activation in Clinical Trials

Teaser label

Industry

Content type

Blogs

Publish date

10/28/2025

Summary

Precision at the Outset: The Strategic Role of Site Selection and Activation in Clinical Trials The success of any clinical trial begins well before the first patient is enrolled. Behind every sit

Teaser label

Explore the critical role of site selection and activation in clinical trials.

Read more
View all

Similar jobs at ICON

CRA II or Senior CRA - Belém do Pará (FSP / Sponsor Dedicated)

Salary

Location

Brazil, Sao Paulo

Location

Sao Paulo

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

We are currently seeking a Clinical Research Associate II or Senior CRA to join our diverse and dynamic team. As a Clinical Research Associate II or Senior CRA at ICON, you will play a pivotal role in

Reference

JR138152

Expiry date

01/01/0001

Tulio Sanquiz

Author

Tulio Sanquiz
Tulio Sanquiz

Author

Tulio Sanquiz
Read more Shortlist Save this role
Read more Shortlist Save this role
CRA II

Salary

Location

Brazil, Sao Paulo

Location

Sao Paulo

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

We are currently seeking a Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate II at ICON, you will play a pivotal role in designing and analyzing cli

Reference

JR139334

Expiry date

01/01/0001

Bruna Duarte

Author

Bruna Duarte
Bruna Duarte

Author

Bruna Duarte
Read more Shortlist Save this role
Read more Shortlist Save this role
Patient Recruitment Associate I

Salary

Location

US, Rocky Mount, NC

Department

Accellacare Site Network

Location

Rocky Mount

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Patient Recruitment

Job Type

Temporary Employee

Description

We have an incredible opportunity for a Patient Recruitment Associate (PRA) to join ICON’s Accellacare team, on a 6-month contract. The PRA is integral to support the growth and success of Accellacare

Reference

JR133498

Expiry date

01/01/0001

Tallulah Pierre

Author

Tallulah Pierre
Tallulah Pierre

Author

Tallulah Pierre
Read more Shortlist Save this role
Read more Shortlist Save this role
Project Assistant Imaging

Salary

Location

Mexico, Mexico City

Department

Full Service - Development & Commercialisation Solutions

Location

Mexico City

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Medical Imaging

Job Type

Permanent

Description

We are currently seeking a Project Assistant, Imaging to join our diverse and dynamic team. As a Project Assistant in Imaging at ICON, you will provide crucial support to the imaging project teams by

Reference

JR138621

Expiry date

01/01/0001

Diego Tonini

Author

Diego Tonini
Diego Tonini

Author

Diego Tonini
Read more Shortlist Save this role
Read more Shortlist Save this role
Senior Patient Recruitment Lead

Salary

Location

US, Downers Grove, IL

Department

Accellacare Site Network

Location

Downers Grove

Blue Bell

Remote Working

Office or Home

Business Area

ICON Full Service & Corporate Support

Job Categories

Patient Recruitment

Job Type

Permanent

Description

This role is with Accellacare, part of ICON's clinical research network, where you’ll play a key role in transforming the clinical trial experience for patients and sponsors alike. Our global site net

Reference

JR136515

Expiry date

01/01/0001

Tallulah Pierre

Author

Tallulah Pierre
Tallulah Pierre

Author

Tallulah Pierre
Read more Shortlist Save this role
Read more Shortlist Save this role
Project Manager, PCS

Salary

Location

France, Lyon

Department

Language Services

Location

Lyon

Remote Working

Office or Home

Business Area

ICON Full Service & Corporate Support

Job Categories

Project/ Program Management

Job Type

Contractor

Description

We are currently seeking a Project Manager, PCS to join our diverse and dynamic team. As a Project Manager, PCS at ICON, you will be responsible for overseeing the implementation and management of Pat

Reference

JR137164

Expiry date

01/01/0001

Jaziara Hancox

Author

Jaziara Hancox
Jaziara Hancox

Author

Jaziara Hancox
Read more Shortlist Save this role
Read more Shortlist Save this role
View Jobs

Browse popular job categories below or search all jobs above