JUMP TO CONTENT
Shortlist
search jobs Search

Our Culture Application Process Career Resources Our Mission & Values

Principal Statistician - Europe home based or office based

JR062558

About the role

This vacancy has now expired. Please click here to view live vacancies.
Principal Biostatistician
ICON is a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries. We specialize in the strategic development, management and analysis of programs that support Clinical Development - from compound selection to Phase I-IV clinical studies.
Position Summary
This position will be accountable for the leadership of the Biostatistics and Programming activities of a program of studies of moderate complexity and/or of high value with high impact for the organization. Also responsible for planning, monitoring, organizing and reviewing activities of biostatisticians and programmers working on the assigned program of studies, ensuring individual studies and the overall program of studies and integrated analyses are delivered on time, on budget to required quality. Accountabilities also include maintenance of consistency across studies. Role could be based at our North Wales office or Home based.
Responsibilities:
  • Accountable for leading Biostatistics and Programming activities for a program of studies of high complexity and/or of high value with high impact.
  • Bio statistical input into the design of the program, Protocol input such as study design, sample size calculations and patient randomization schemes and Statistical aspects of case report form design
  • Review project database structures, edit checks and data management coding conventions
  • Preparation of statistical analysis plans including the definition of derived data, and the design of statistical tables, figures, and data listings for clinical summary reports
  • Statistical analysis, Interpretation of data and reporting of results.
  • Writing of the statistical methods sections of integrated study reports. Reviews draft integrated study reports.
  • Supports responses to regulatory questions on the design of the program, and any labelling claims following submission
  • Participates in presentations at client and investigator meetings.
  • Preparation of biostatistics input to ICON research proposals, and participates in proposal defense meetings and makes presentations at marketing meetings with prospective client.
  • Ongoing coaching and mentorship of team members.

Key Requirements:
  • M.S. degree in statistics, biostatistics, with relevant experience in the pharmaceutical industry or Ph.D. in statistics, biostatistics
  • Experience with oncology is required
  • In-depth knowledge of study designs, and statistical analysis applications in one or more therapeutic areas.
  • Excellent verbal and written communication skills as well as interpersonal and project management skills
  • Excellent knowledge of a wide variety of principles, theories and concepts in statistics and experimental design; must be able to apply them to the development and analysis of clinical trials
  • Excellent knowledge of clinical trials methodology, regulatory requirements, statistics and statistical software packages, including SAS are a must.
  • Experience leading a regulatory submission
  • Must be able to translate clients' needs into statistical practice and educate clients in the use of statistics.
List #1

Day in the life

Headshot image of male
Driving Trials Forward: Study Start-Up Leadership at ICON

Teaser label

Our People

Content type

Blogs

Publish date

03/16/2026

Summary

Driving Study Start-Up: James Pereira's Journey at ICON James Pereira's career in clinical research has been shaped by a single driving question: how do we get studies started faster? From his earl

Teaser label

Explore James Pereira's career in study start-up at ICON, leading global teams to accelerate patient access.

Read more
Male and female in lab
Who’s Who in a Clinical Trial Team

Teaser label

Inside ICON

Content type

Blogs

Publish date

03/15/2026

Summary

Who's Who In a Clinical Trial Team Clinical trials rely on large, cross functional teams working together across countries, time zones and specialisms. For those new to the industry, the number of

Teaser label

Understand the key roles in a clinical trial team, from study start up and site activation to data, safety and quality.

Read more
Nurse and patient
Understanding Roles in a Clinical Trial: Sponsors, CROs, and Sites

Teaser label

Industry

Content type

Blogs

Publish date

02/16/2026

Summary

What Sponsors, CROs, and Sites Each Do Clinical research brings together many organisations, each with a specific role in delivering a clinical trial. For those new to the industry, the relationsh

Teaser label

Learn how clinical trials are delivered by understanding the roles of sponsors, CROs, and sites.

Read more
View all

Similar jobs at ICON

Global CTA

Salary

Location

UK, Reading

Location

Warsaw

Madrid

Reading

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Operations

Job Type

Permanent

Description

We are currently seeking a Global CTA to join our diverse and dynamic team. As a global CTA at ICON, you will assist with local project management activities of a clinical trials in a country or count

Reference

JR147167

Expiry date

01/01/0001

Rajvir Samra

Author

Rajvir Samra
Rajvir Samra

Author

Rajvir Samra
Read more Shortlist Save this role
Read more Shortlist Save this role
CTA

Salary

Location

Spain, Madrid

Location

Sofia

Warsaw

Bucharest

Madrid

Gdansk

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

We are currently seeking a CTA to join our diverse and dynamic team. As a CTA at ICON you will play a pivotal role in assisting with the design and analysis of clinical trials, interpreting complex me

Reference

JR146710

Expiry date

01/01/0001

Salome Kankia

Author

Salome Kankia
Salome Kankia

Author

Salome Kankia
Read more Shortlist Save this role
Read more Shortlist Save this role
Pharmacy Technician

Salary

Location

Netherlands, Groningen GRQM

Department

Full Service - Early Clinical and Bioanalytical Solutions

Location

Groningen

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Pharmacy

Job Type

Permanent

Description

Job Advert PostingApothekersassistent – ICON Groningen32, 36 of 40 uur per week | Salaris en arbeidsvoorwaarden volgens ICON CAOBij ICON draag je bij aan de ontwikkeling van de geneesmiddelen van de t

Reference

JR141940

Expiry date

01/01/0001

Sophia Cairns

Author

Sophia Cairns
Sophia Cairns

Author

Sophia Cairns
Read more Shortlist Save this role
Read more Shortlist Save this role
Data Manager - Digital Health Technologies

Salary

Location

UK, Reading

Location

Madrid

Reading

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Project Management

Job Type

Permanent

Description

We are currently seeking a Medical Informatics Manager to join our diverse and dynamic team.We are looking for a self-directed professional to support clinical data management efforts for the Biomeasu

Reference

JR146921

Expiry date

01/01/0001

Rajvir Samra

Author

Rajvir Samra
Rajvir Samra

Author

Rajvir Samra
Read more Shortlist Save this role
Read more Shortlist Save this role
CTA

Salary

Location

China, Shanghai

Location

Shanghai

Remote Working

Hybrid

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

We are currently seeking a Clinical Trial Administrator to join our diverse and dynamic team. As a Clinical Trial Administrator at ICON, you will play a pivotal role in assisting with the design and a

Reference

JR147215

Expiry date

01/01/0001

Huixin "Stella" Song

Author

Huixin "Stella" Song
Huixin "Stella" Song

Author

Huixin "Stella" Song
Read more Shortlist Save this role
Read more Shortlist Save this role
Clinical Trail Assocaite

Salary

Location

Israel, Tel Aviv

Location

Tel Aviv

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

We are currently seeking a Clinical Trial Administrator to join our diverse and dynamic team. As a Clinical Trial Administrator at ICON, you will play a pivotal role in assisting with the design and a

Reference

JR147183

Expiry date

01/01/0001

Salome Kankia

Author

Salome Kankia
Salome Kankia

Author

Salome Kankia
Read more Shortlist Save this role
Read more Shortlist Save this role
View Jobs

Browse popular job categories below or search all jobs above