Principal Statistician - Europe home based or office based job in

This vacancy has now expired. Please click here to view live vacancies.

Principal Biostatistician

ICON is a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries. We specialize in the strategic development, management and analysis of programs that support Clinical Development - from compound selection to Phase I-IV clinical studies.

Position Summary

This position will be accountable for the leadership of the Biostatistics and Programming activities of a program of studies of moderate complexity and/or of high value with high impact for the organization. Also responsible for planning, monitoring, organizing and reviewing activities of biostatisticians and programmers working on the assigned program of studies, ensuring individual studies and the overall program of studies and integrated analyses are delivered on time, on budget to required quality. Accountabilities also include maintenance of consistency across studies. Role could be based at our North Wales office or Home based.

Responsibilities:

Accountable for leading Biostatistics and Programming activities for a program of studies of high complexity and/or of high value with high impact.
Bio statistical input into the design of the program, Protocol input such as study design, sample size calculations and patient randomization schemes and Statistical aspects of case report form design
Review project database structures, edit checks and data management coding conventions
Preparation of statistical analysis plans including the definition of derived data, and the design of statistical tables, figures, and data listings for clinical summary reports
Statistical analysis, Interpretation of data and reporting of results.
Writing of the statistical methods sections of integrated study reports. Reviews draft integrated study reports.
Supports responses to regulatory questions on the design of the program, and any labelling claims following submission
Participates in presentations at client and investigator meetings.
Preparation of biostatistics input to ICON research proposals, and participates in proposal defense meetings and makes presentations at marketing meetings with prospective client.
Ongoing coaching and mentorship of team members.

Key Requirements:

M.S. degree in statistics, biostatistics, with relevant experience in the pharmaceutical industry or Ph.D. in statistics, biostatistics
Experience with oncology is required
In-depth knowledge of study designs, and statistical analysis applications in one or more therapeutic areas.
Excellent verbal and written communication skills as well as interpersonal and project management skills
Excellent knowledge of a wide variety of principles, theories and concepts in statistics and experimental design; must be able to apply them to the development and analysis of clinical trials
Excellent knowledge of clinical trials methodology, regulatory requirements, statistics and statistical software packages, including SAS are a must.
Experience leading a regulatory submission
Must be able to translate clients' needs into statistical practice and educate clients in the use of statistics.

Impactful work. Meaningful careers. Quality rewards.

At ICON, our employees are our greatest strength. That’s why we are committed to empowering you to live your best life, both inside and outside of work. Whether your ambition is lead a global team, become a deep scientific or technical expert, work in-house with our customers or gain experience in a variety of different ICON functions, we will support you in realising your full potential.
See all locations

Learn more about Our Culture at ICON

List #1

Day in the life

Networking Strategies in Clinical Research

Teaser label

Industry

Content type

Blogs

Publish date

06/06/2025

Summary

Building Connections that Drive Progress In an industry where collaboration is critical to advancing science and improving patient outcomes, networking is more than a professional courtesy - it’s

Teaser label

Discover how strategic networking can strengthen collaboration, and support your clinical research career journey.

Blood Cancer Day - Raising Awareness and Driving Change

Teaser label

Industry

Content type

Blogs

Publish date

05/29/2025

Summary

Blood Cancer Day Blood Cancer Day is a powerful reminder of the millions of individuals and families whose lives are affected by hematological malignancies every year. These diseases are complex,

Teaser label

Learn how clinical research is transforming the future for those affected by hematological cancers.

Recognising World Schizophrenia Day through Research and Compassion

Teaser label

Industry

Content type

Blogs

Publish date

05/22/2025

Summary

World Schizophrenia Awareness Day 2025 Every year on 24 May, World Schizophrenia Awareness Day offers a vital opportunity to raise awareness, dismantle stigma, and celebrate the strength of individ

Teaser label

Explore how ICON is advancing schizophrenia research and addressing stigma through clinical innovation.

View all

Similar jobs at ICON

Study Support Assistant

Salary

Location

Mexico City

Department

Study Start Up

Location

Mexico City

Business Area

ICON Strategic Solutions

Job Categories

Study Start Up

Job Type

Permanent

Description

As a Study Support Assistant you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence

Reference

2025-120464

Expiry date

01/01/0001

Author

Rita Villavicencio

Author

Rita Villavicencio

Read more Shortlist Save this role

Clinical Study Manager II

Salary

Location

Mexico

Department

Clinical Trial Management

Location

Mexico

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Management

Job Type

Permanent

Description

As a Clinical Trials Laboratory Manager you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence. You will be partnering with a p

Reference

2025-120444

Expiry date

01/01/0001

Author

Rita Villavicencio

Author

Rita Villavicencio

Read more Shortlist Save this role

Clinical Study Manager II

Salary

Location

Mexico

Department

Clinical Trial Management

Location

Mexico

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Management

Job Type

Permanent

Description

Reference

2025-120445

Expiry date

01/01/0001

Author

Rita Villavicencio

Author

Rita Villavicencio

Read more Shortlist Save this role

Senior Medical Writer

Salary

Location

Canada

Department

Medical Affiars & Medical Writing Roles

Location

Canada

Remote Working

Home-Based

Business Area

ICON Strategic Solutions

Job Categories

Medical Writing

Job Type

Permanent

Description

As a Senior Medical Writer you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-120484

Expiry date

01/01/0001

Author

Brendan Hoey

Author

Brendan Hoey

Read more Shortlist Save this role

Senior Regulatory Operations Associate - Fixed Term Position

Salary

Location

Brazil, Sao Paulo

Location

Sao Paulo

Mexico City

Remote Working

Home or Office

Business Area

ICON Full Service & Corporate Support

Job Categories

Drug / Device Regulatory Affairs

Job Type

Temporary Employee

Description

At ICON, it’s our people that set us apart. Our diverse teams enable us to become a better partner to our customers and help us to fulfil our mission to advance and improve patients’ lives. Our ‘Own I

Reference

JR131937

Expiry date

01/01/0001

Author

Ana Lucia

Author

Ana Lucia

Read more Shortlist Save this role

Clinical Study Manager II

Salary

Location

Mexico

Department

Clinical Trial Management

Location

Mexico

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Management

Job Type

Permanent

Description

Reference

2025-119447

Expiry date

01/01/0001

Author

Rita Villavicencio

Author

Rita Villavicencio

Read more Shortlist Save this role

About Icon

Overview of Service Lines

Full Service

ICON Strategic Solutions

Government and public health services

Global Business Services

Overview of Service Lines

Global Office Locator

Inclusion & Belonging

ICON Cares - ESG

Why icon? full service mean for you?

Building a Successful Clinical Research Resume

Landing Your First Job in Clinical Research

graduate What does full service mean for you?

Principal Statistician - Europe home based or office based

About the role

This vacancy has now expired. Please click here to view live vacancies.

ICON and you

About ICON

Career Pathways

Benefits & Rewards

Inclusion & Belonging

Environmental, Social & Governance

Global Office Locator

Impactful work. Meaningful careers. Quality rewards.

About Icon

Overview of Service Lines

Government and public health services

Global Office Locator

Inclusion & Belonging

ICON Cares - ESG

Why icon? full service mean for you?

Building a Successful Clinical Research Resume

Landing Your First Job in Clinical Research

Principal Statistician - Europe home based or office based

Send me a message

About the role

This vacancy has now expired. Please click here to view live vacancies.

ICON and you

About ICON

Career Pathways

Benefits & Rewards

Inclusion & Belonging

Environmental, Social & Governance

Global Office Locator

Impactful work. Meaningful careers. Quality rewards.