JUMP TO CONTENT
Shortlist
search jobs Search

Our Culture Application Process Career Resources Our Mission & Values

Principal Statistician - Europe home based or office based

JR062558

About the role

This vacancy has now expired. Please click here to view live vacancies.
Principal Biostatistician
ICON is a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries. We specialize in the strategic development, management and analysis of programs that support Clinical Development - from compound selection to Phase I-IV clinical studies.
Position Summary
This position will be accountable for the leadership of the Biostatistics and Programming activities of a program of studies of moderate complexity and/or of high value with high impact for the organization. Also responsible for planning, monitoring, organizing and reviewing activities of biostatisticians and programmers working on the assigned program of studies, ensuring individual studies and the overall program of studies and integrated analyses are delivered on time, on budget to required quality. Accountabilities also include maintenance of consistency across studies. Role could be based at our North Wales office or Home based.
Responsibilities:
  • Accountable for leading Biostatistics and Programming activities for a program of studies of high complexity and/or of high value with high impact.
  • Bio statistical input into the design of the program, Protocol input such as study design, sample size calculations and patient randomization schemes and Statistical aspects of case report form design
  • Review project database structures, edit checks and data management coding conventions
  • Preparation of statistical analysis plans including the definition of derived data, and the design of statistical tables, figures, and data listings for clinical summary reports
  • Statistical analysis, Interpretation of data and reporting of results.
  • Writing of the statistical methods sections of integrated study reports. Reviews draft integrated study reports.
  • Supports responses to regulatory questions on the design of the program, and any labelling claims following submission
  • Participates in presentations at client and investigator meetings.
  • Preparation of biostatistics input to ICON research proposals, and participates in proposal defense meetings and makes presentations at marketing meetings with prospective client.
  • Ongoing coaching and mentorship of team members.

Key Requirements:
  • M.S. degree in statistics, biostatistics, with relevant experience in the pharmaceutical industry or Ph.D. in statistics, biostatistics
  • Experience with oncology is required
  • In-depth knowledge of study designs, and statistical analysis applications in one or more therapeutic areas.
  • Excellent verbal and written communication skills as well as interpersonal and project management skills
  • Excellent knowledge of a wide variety of principles, theories and concepts in statistics and experimental design; must be able to apply them to the development and analysis of clinical trials
  • Excellent knowledge of clinical trials methodology, regulatory requirements, statistics and statistical software packages, including SAS are a must.
  • Experience leading a regulatory submission
  • Must be able to translate clients' needs into statistical practice and educate clients in the use of statistics.
List #1

Day in the life

video job interview
Interviewing at ICON

Teaser label

Inside ICON

Content type

Blogs

Publish date

01/05/2026

Summary

Interviewing at ICON: What to Expect Applying for a new role can feel uncertain, particularly when recruitment processes use digital tools or assessments that may be unfamiliar. At ICON, we want ca

Teaser label

Learn what to expect when interviewing at ICON, and how hiring decisions are always made by people.

Read more
Job application note
Applying to ICON: How Workday’s ATS Works and How to Stand Out

Teaser label

Inside ICON

Content type

Blogs

Publish date

01/05/2026

Summary

What is an Applicant Tracking System (ATS)? An Applicant Tracking System (ATS) is software used by organisations to manage the recruitment process from job posting through to hiring. It acts as a

Teaser label

Learn how ICON uses Workday’s applicant tracking system (ATS), what recruiters see, and how to optimise your application.

Read more
Headshot of male
Leading Through Change: Zhong Yao's Journey at ICON in China

Teaser label

Our People

Content type

Blogs

Publish date

12/10/2025

Summary

Zhong Yao's Journey at ICON Plc in China Zhong Yao's career in clinical research spans over two decades, with leadership roles across major CROs and a commitment to advancing healthcare in China.

Teaser label

From culture to collaboration, Zhong Yao explains how ICON China delivers quality clinical trials, and empowers local talent.

Read more
View all

Similar jobs at ICON

Sr. Clinical Research Associate

Salary

Location

Calgary

Location

Calgary

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

We are currently seeking a Senior Clinical Research Associate (CRA) to join our diverse and dynamic team. As a Senior CRA at ICON Plc, you will play a critical role in overseeing and managing clinical

Reference

JR140647

Expiry date

01/01/0001

Melissa Benner

Author

Melissa Benner
Melissa Benner

Author

Melissa Benner
Read more Shortlist Save this role
Read more Shortlist Save this role
Senior Manager, Central Support Services

Salary

Location

UK, Swansea

Location

Swansea

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Trial Management

Job Type

Permanent

Description

We are currently seeking a Senior Manager, Central Support Services to join our diverse and dynamic team in Swansea, As a Senior Manager, Central Support Services at ICON, you will be crucial in overs

Reference

JR137597

Expiry date

01/01/0001

Sophia Cairns

Author

Sophia Cairns
Sophia Cairns

Author

Sophia Cairns
Read more Shortlist Save this role
Read more Shortlist Save this role
Global Clinical Trial Assistant, Hematology

Salary

Location

Spain, Madrid

Location

Paris

Warsaw

Barcelona

Madrid

Reading

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

As the world’s largest provider of Functional Service Provision (FSP), ICON Strategic Solutions embeds our teams within client organisations, serving as dedicated partners to some of the world’s leadi

Reference

JR138144

Expiry date

01/01/0001

Tanzina Guerni

Author

Tanzina Guerni
Tanzina Guerni

Author

Tanzina Guerni
Read more Shortlist Save this role
Read more Shortlist Save this role
Principal Medical Writer

Salary

Location

France, Paris

Location

Paris

Remote Working

Office or Home

Business Area

ICON Strategic Solutions

Job Categories

Medical Writing

Job Type

Permanent

Description

We are currently seeking Senior or Principal Medical Writer to join our diverse and dynamic team. At this role you will be responsible for leading the development of high-quality regulatory and clinic

Reference

JR141644

Expiry date

01/01/0001

Natalia Roth

Author

Natalia Roth
Natalia Roth

Author

Natalia Roth
Read more Shortlist Save this role
Read more Shortlist Save this role
Senior Project Manager, IT

Salary

Location

Ireland, Dublin

Department

Information technology

Location

Dublin

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Technical Project Management

Non-Clinical Project Management

Job Type

Permanent

Description

We are currently seeking a Senior Project Manager to join our diverse and dynamic team. As a Senior Project Manager, IT at ICON, you will be responsible for leading and managing IT projects, ensuring

Reference

JR140976

Expiry date

01/01/0001

Maya Katsarska

Author

Maya Katsarska
Maya Katsarska

Author

Maya Katsarska
Read more Shortlist Save this role
Read more Shortlist Save this role
Clinical Packaging Technician - First Shift

Salary

Location

West Point, PA

Location

West Point, PA

Remote Working

Office Based

Business Area

ICON Strategic Solutions

Job Categories

Project/ Program Management

Job Type

Permanent

Description

We are currently seeking a Clinical Packaging Technician to join our diverse and dynamic team. As a CPT at ICON, you will play a pivotal role in providing key administrative support in clinical operat

Reference

JR141510

Expiry date

01/01/0001

Brandon Pupek

Author

Brandon Pupek
Brandon Pupek

Author

Brandon Pupek
Read more Shortlist Save this role
Read more Shortlist Save this role
View Jobs

Browse popular job categories below or search all jobs above