Sr. Clinical Trial Manager - CNS/Rare Diseases (Home-based)
About the role
This vacancy has now expired. Please click here to view live vacancies.
As a global provider of drug development solutions, our work is serious business. But that doesn't mean you can't have fun while you do it. With our vision to be the partner of choice in drug development, we hire only the best and brightest in the industry! Are you one of them?
At ICON, we have an incredible opportunity for an expert Sr. Clinical Trial Manager to join the team in the US.
The Role:
The Sr. Clinical Trial Manager is responsible for the delivery of all clinical aspects of the study. The CTM oversees the clinical portion of the budget, develops monitoring plans & tools, trains CRAs, drives enrolment and study start-up activities, reviews trip reports, implements corrective and preventative action plans, liaises with the Sponsor, vendors & cross-functional teams, identifies & mitigates risks that may impact clinical delivery, and provides reporting & metrics on all clinical activities. The CTM will also participate in Sponsor, Investigator and bid defense meetings.
What you need:
- 4 year degree or equivalent combination of education & experience
- Demonstrated ability to drive the clinical deliverables of a study
- Subject matter expertise in CNS and/or Rare Diseases
- Prior monitoring experience is preferred
- Ability to travel up to 20%
- Fluent in local language - both written & verbal
Why join us?
Other than working with an outstanding team of ambitious people, we also offer a very competitive benefits package. This varies from country to country so a dedicated recruiter will discuss this with you at interview stage.
We care about our people as they are the key to our success. We provide an open and friendly work environment where we empower people and provide them with opportunities to develop their long term career.
Ongoing development is vital to us, and as a Clinical Trial Manager, you will have the opportunity to progress your career, with the potential to move into other related areas to improve your skillset. Our benefits package is competitive, our scope is international and we sincerely care about our people and their success.
ICON is an equal opportunity employer and committed to providing a workplace free of any discrimination or harassment.
EOE race/color/religion/sex/sexual orientation/gender identity/disability/vet/national origin
Explore more about ICON
Day in the life
Teaser label
Our PeopleContent type
BlogsPublish date
06/10/2026
Summary
Why I Still Recommend the CTA Role After More Than 10 Years in Clinical Research Clinical Operations Manager Yordan Zahariev reflects on career growth, leadership and the opportunities a CTA role
Teaser label
Our PeopleContent type
BlogsPublish date
06/04/2026
Summary
After more than 20 years at ICON, Carolina Boari has witnessed the organisation's growth across Latin America while building a successful career of her own. Today, as Executive Director of Clini
Teaser label
Our PeopleContent type
BlogsPublish date
05/26/2026
Summary
From Data Management to Leadership For Sajna Basant, a career in Biometrics has always been about more than data. “Data is not just numbers,” she explains. “It represents real people, their health
Similar jobs at ICON
Salary
Location
Italy, Milan
Location
Milan
Remote Working
Remote
Business Area
ICON Strategic Solutions (FSP)
Job Categories
Clinical Monitoring
Job Type
Permanent
Description
As a CRA at ICON, you will design and analyse clinical trials, interpreting complex medical data, and contribute to the advancement of innovative treatments and therapies.What You Will Do:You will con
Reference
JR155018
Expiry date
01/01/0001
Author
Mattia CarcangiuAuthor
Mattia CarcangiuSalary
Location
UK, Swansea
Location
Dublin
Warsaw
Barcelona
Madrid
Reading
Gdansk
Swansea
Remote Working
Remote or Office
Business Area
ICON Full Service & Corporate Support
Job Categories
Clinical Data Management
Data Science
Job Type
Permanent
Description
As a Senior Clinical Data Science Lead at ICON, you will lead the analysis, interpretation, and management of clinical data to drive the success of our clinical trials.What You Will Do:You will overse
Reference
JR153191
Expiry date
01/01/0001
Author
Sophia CairnsAuthor
Sophia CairnsSalary
Location
France, Paris
Location
Paris
Remote Working
Remote or Office
Business Area
ICON Strategic Solutions (FSP)
Job Categories
Clinical Monitoring
Job Type
Permanent
Description
As a Study Start-Up CRA at ICON, you will design and analyse clinical trials, interpreting complex medical data, and contribute to the advancement of innovative treatments and therapies. For this role
Reference
JR150894
Expiry date
01/01/0001
Author
Sebastien Bechara
Author
Sebastien BecharaSalary
Location
Italy, Milan
Location
Milan
Remote Working
Remote
Business Area
ICON Strategic Solutions (FSP)
Job Categories
Clinical Monitoring
Job Type
Permanent
Description
As a Senior CRA at ICON Plc, you will oversee and manage clinical trial activities to ensure they are conducted according to protocol, regulatory requirements, and industry standards. What You Will Do
Reference
JR155173
Expiry date
01/01/0001
Author
Mattia CarcangiuAuthor
Mattia CarcangiuSalary
Location
Italy, Milan
Location
Milan
Remote Working
Remote
Business Area
ICON Strategic Solutions (FSP)
Job Categories
Clinical Monitoring
Job Type
Permanent
Description
As a CRA I at ICON, you will contribute to our clinical trial operations function, working collaboratively to deliver high-quality outcomes across our clinical programmes. What You Will Do:Your role w
Reference
JR155172
Expiry date
01/01/0001
Author
Mattia CarcangiuAuthor
Mattia CarcangiuSalary
Location
Taiwan, Taipei
Location
Taipei
Remote Working
Remote
Business Area
ICON Strategic Solutions (FSP)
Job Categories
Project/ Program Management
Job Type
Permanent
Description
We are seeking an experienced (Senior) Translation Project Manager to lead the planning, coordination, and delivery of clinical document translations in a highly regulated global environment. This rol
Reference
JR155233
Expiry date
01/01/0001
Author
Sandy TangAuthor
Sandy Tang