JUMP TO CONTENT

Principal Scientist

JR072294

About the role

This vacancy has now expired. Please click here to view live vacancies.

*Recognize, exemplify and adhere to ICON's values which centers around our commitment to People, Clients and Performance.
* As a member of staff, the employee I expected to embrace and contribute to our culture of process improvement with a focus on streamlining our processes adding value to our business and meeting client needs.
* Travel (approximately 1%) domestic and/or international.
* *Perform Bioanalytical method development and method validation for the quantification of NCE, NBE and Biomarkers in tissues and biological fluids.
* * Work with clients to bring externally established assays and technologies in-house and/or transfer in-house assays externally as required.
* Prepare Bioanalytical method documents.
* *May manage analytical studies and act as scientific consultant to clients, and internal scientific consultant within Icon.
* *Work with laboratory management to ensure that appropriate resources are available to complete the study to timeline. May obtain all client specific documents required for the analysis, ie study protocol, randomization lists, COA, demographic etc
* *Prepare analysis plans suitable to the clients needs and obtain client approval of these.
* *Supervise analytical teams to ensure that study plans and validation plans, as appropriate are complied with.
* *Work with clients to ensure studies are conducted in a manner compliant with the clients stated needs as defined by contract, and that the project delivery, reporting specifics, timelines agreed to are met. Inform DM and QC/QA of deadlines.
* *Where appropriate, prepare invoice requests at agreed milestones ensuring that both ICON finance and the client has all necessary information to allow the invoice to be approved for payment.
* *Maintain records of work conducted in a timely and consistent manner, sufficient to allow real-time tracking of the deliverables, including tracking of revenue and resources associated with assigned studies. Inform stakeholder of changes to scope or timelines.
* Identify changes to scope of work and notify contracts of need for change order.
* *Review all data in accordance with direction documents and ensure results are documented accurately, completely and compliant with GLP/GCP regulations and SOPs .
* *Assist Project Leaders and lab staff in proactively identifying possible/potential implications of unusual results. Assist as required in an investigation and report findings.
* *Perform assay for the routine batch analysis of NCE, NBE and Biomarkers in tissues and biological fluids involving simple and complex analytical techniques. Perform laboratory work to GLP/GCP standard.
* *Document all work and results accurately, completely and compliant with GXP regulations and SOP's.
* *Generate high quality analytical results. Ensure smooth transfer of data to PI's and participate in evaluation and interpretation of data.
* *Lead investigations of instrumental and procedural problems.
* *Evaluate new equipment or technologies and make recommendations to management on utility for the laboratory and business.
* Approve release of method development and non-GXP data
* *Prepare reports (or oversee as appropriate) of the work conducted, address all QA findings and provide QA draft report in line with the terms and conditions stated in the signed contract.
* Ensure that all documentation is appropriately archived on completion of the study.
* *Check and verify laboratory notebooks and other analytical data as required.
* *Author SOPs as needed. Maintain awareness of and adherence to all current SOPs.
* *Work in compliance with GXP.
* All other duties as needed.

List #1

Day in the life

Blood cancer cells
Blood Cancer Day - Raising Awareness and Driving Change

Teaser label

Industry

Content type

Blogs

Publish date

05/29/2025

Summary

Blood Cancer Day Blood Cancer Day is a powerful reminder of the millions of individuals and families whose lives are affected by hematological malignancies every year. These diseases are complex,

Teaser label

Learn how clinical research is transforming the future for those affected by hematological cancers.

Read more
Silver ribbon
Recognising World Schizophrenia Day through Research and Compassion

Teaser label

Industry

Content type

Blogs

Publish date

05/22/2025

Summary

World Schizophrenia Awareness Day 2025 Every year on 24 May, World Schizophrenia Awareness Day offers a vital opportunity to raise awareness, dismantle stigma, and celebrate the strength of individ

Teaser label

Explore how ICON is advancing schizophrenia research and addressing stigma through clinical innovation.

Read more
Ovarian cancer knot being held in woman's hands
Standing Strong on Ovarian Cancer Day

Teaser label

Inside ICON

Content type

Blogs

Publish date

05/08/2025

Summary

Standing Strong on Ovarian Cancer Day:    ICON's Commitment to Advancing Care Ovarian cancer remains one of the most challenging gynaecologic malignancies, both in terms of detection and treatmen

Teaser label

Martin Lachs, VP, Oncology Project Management at ICON discusses ICON’s role in advancing ovarian cancer research.

Read more
View all

Similar jobs at ICON

Intern - IHCRA

Salary

Location

Czech Republic, Prague

Department

Clinical Monitoring

Location

Prague

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Intern

Job Type

Intern

Description

We are currently seeking an Intern to join our diverse and dynamic team. As an Intern at ICON, you will have the opportunity to gain hands-on experience in a professional environment, supporting vario

Reference

JR131143

Expiry date

01/01/0001

Lauren Pritchett Read more Shortlist Save this role
Program Manager, Labs

Salary

Location

US, Blue Bell (ICON)

Department

Full Service - Development & Commercialisation Solutions

Full Service - Global Business Services

Location

New York

Blue Bell

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Project/ Program Management

Job Type

Permanent

Description

Program Manager, Labs – Blue Bell PA, Farmingdale NY- Hybrid.    Assist the team of PMs in issue resolution / escalation during the lifetime of all trials  • Understand your Project Managers’ performa

Reference

JR130137

Expiry date

01/01/0001

Frank Lampart

Author

Frank Lampart
Read more Shortlist Save this role
Surgical Science Liaison (Neurosurgery)

Salary

Location

United States

Department

Regulatory, Drug Safety/ Quality Assurance & Other roles

Location

United States

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Other

Job Type

Permanent

Description

As a Surgical Science Liaison (Neurosurgery) – Part-time/Contract, you will join the world’s largest and most comprehensive clinical research organization, driven by healthcare intelligence.

Reference

2025-119361

Expiry date

01/01/0001

Read more Shortlist Save this role
Lab Analyst II

Salary

Location

US, Lenexa KCI (PRA)

Department

Full Service - Early Clinical and Bioanalytical Solutions

Location

Lenexa

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Laboratory Support

Job Type

Temporary Employee

Description

We are currently seeking a Lab Analyst II to join our diverse and dynamic team. As a Lab Analyst II at ICON, you will be responsible for performing intermediate-level laboratory tests and analyses to

Reference

JR127410

Expiry date

01/01/0001

Kahla Cureton

Author

Kahla Cureton
Read more Shortlist Save this role
HR Advisor

Salary

Location

Mexico, Mexico City

Department

Full Service - Corporate Support

Location

Mexico City

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

HR Advisor

Job Type

Permanent

Description

Hybrid Role: 3 days in the office / 2 days remote (home office)Location: Insurgentes Sur, Mexico CityWe are currently seeking an HR Advisor to join our diverse and dynamic team supporting our Canadian

Reference

JR131083

Expiry date

01/01/0001

Daniela Guerrero Read more Shortlist Save this role
Manager, PK Laboratory

Salary

Location

US, Lenexa KCI (PRA)

Department

Full Service - Early Clinical and Bioanalytical Solutions

Location

Lenexa

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Laboratory

Job Type

Permanent

Description

We are currently seeking a Manager, PK Laboratory to join our diverse and dynamic team. As a Manager, PK Laboratory at ICON, you will be responsible for overseeing all pharmacokinetics (PK) laboratory

Reference

JR128689

Expiry date

01/01/0001

Kahla Cureton

Author

Kahla Cureton
Read more Shortlist Save this role
View Jobs

Browse popular job categories below or search all jobs above