Senior Manager, Bioanalytical Services- Onsite, Lenexa, KS
ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
At ICON, it’s our people that set us apart. Our diverse teams enable us to become a better partner to our customers and help us to fulfil our mission to advance and improve patients’ lives.
Our ‘Own It’ culture is driven by four key values that bring us together as individuals and set us apart as an organization: Accountability & Delivery, Collaboration, Partnership and Integrity. We want to be the Clinical Research Organization that delivers excellence to our clients and to patients at every touch-point. In short, to be the partner of choice in drug development.
That’s our vision. We’re driven by it. And we need talented people who share it.
If you’re as driven as we are, join us. You’ll be working in a dynamic and supportive environment, with some of the brightest and the friendliest people in the sector, and you’ll be helping shape an industry.
Senior Manager, Bioanalytical Services LC-MS/MS Operations- Bioanalytical Services
Onsite: Lenexa, KS
Full-Time Opportunity
We are seeking a Senior Manager of LC-MS/MS Operations to provide scientific and operational leadership for ICON’s Bioanalytical Services team in Lenexa, with a focus on regulated LC-MS/MS studies. This role is responsible for overseeing method development, validation, and regulated sample analysis, ensuring operational excellence, team performance, and client satisfaction within a GLP-compliant environment.
Operational & Scientific Leadership
Lead day-to-day LC-MS/MS laboratory operations and ensure delivery of client studies on time and within quality and regulatory expectations.
Manage workflows involving small molecules, peptides, oligonucleotides, siRNAs, and antibody-drug conjugates (ADCs).
Oversee method development, validation, and sample analysis in compliance with ICH M10 and GLP regulations.
Drive resource planning, instrument utilization, and capacity optimization across LC-MS/MS platforms.
Client Engagement & Business Support
Act as a scientific and operational point-of-contact for sponsors, supporting study design, troubleshooting, and client communications.
Collaborate with Business Development to support growth through technical consultation, capabilities presentations, and project proposals.
Represent LC-MS/MS operations during audits, client meetings, and regulatory inspections.
Compliance & Quality
Ensure adherence to GLP, GCP, and global regulatory standards across all LC-MS/MS studies.
Partner with QA to maintain SOPs, address compliance gaps, and implement quality-driven improvements.
Foster a culture of proactive issue resolution, continuous improvement, and data integrity.
Team Leadership & Development
Mentor and lead a team of scientists, analysts, and lab staff with a focus on performance, scientific excellence, and professional development.
Support onboarding, training, and career progression within the LC-MS/MS group.
Promote a collaborative, inclusive, and solution-oriented work environment aligned with ICON values.
Cross-Functional Collaboration
Work closely with cross-functional teams including LIMS, clinical project management, and other global bioanalytical labs to align strategies and share best practices.
Contribute to department-wide initiatives supporting harmonization and innovation across ICON Bioanalytical Services.
Qualifications & Experience
Required:
PhD degree in Chemistry, Biochemistry, or a related field.
6+ years of experience in regulated LC-MS/MS bioanalysis, including supervisory or leadership experience.
Deep technical knowledge of quantitative LC-MS/MS methods, reverse-phase and size-exclusion chromatography, and regulated bioanalytical workflows.
Proven ability to manage projects, meet timelines, and uphold high scientific standards in a regulated environment.
Preferred:
Experience with automation platforms, LIMS, and electronic laboratory notebooks (ELNs).
Knowledge of CRO operations and client service expectations in a fast-paced environment.
Strong communication, problem-solving, and mentoring skills.
Why Join Us?
At ICON, you’ll be part of a global team dedicated to improving patient outcomes through high-quality science. Join a top-ranked CRO with award-winning culture, growth opportunities, and a commitment to operational excellence and innovation.
Benefits of Working in ICON:
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a culture that rewards high performance and nurtures talent.
We offer very competitive salary packages. And to keep them competitive, we regularly benchmark them against our competitors. Our annual bonuses reflect delivery of performance goals – both ours and yours.
We also provide a range of health-related benefits to employees and their families and offer competitive retirement plans – and related benefits such as life assurance – so you can save and plan with confidence for the years ahead.
But beyond the competitive salaries and comprehensive benefits, you’ll benefit from an environment where you are encouraged to fulfil your sense of purpose and drive lasting change.
ICON is an equal opportunity and inclusive employer and is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know through the form below.
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What ICON can offer you:
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
Our benefits examples include:
- Various annual leave entitlements
- A range of health insurance offerings to suit you and your family’s needs.
- Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
- Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
- Life assurance
- Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.
Visit our careers site to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here
Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.
Are you a current ICON Employee? Please click here to apply
