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Early Phase Services

Strategy & delivery of early-phase clinical development services

Preclinical/Phase 1 specialise in the strategy and delivery of early-phase clinical development services. This enables us to provide informed, timely decisions for our clients.

Our Development Solutions teams have expertise in early phase clinical research, bioanalytics, PK-PD modelling and simulation as well as the full range of supporting services. In everything we do we incorporate scientific excellence and product development strategy.

Our experts are multi-disciplinary and have the experience to address even the most demanding of drug development challenges with an uncompromising focus on completing projects on time, within budget and to a standard that will always shine under even the most critical scrutiny.


In this area our key services include:

• Product development consulting
• Bioanalytical
• PK/PD Modelling and simulation
• Population PK
• Data Analysis (TK, PK, PK/PD)
• Regulatory affairs strategy / submission
• Protocol design 
• Medical Writing
• Quality Control/Assurance
• Pharmacodynamic Models
• Clinical studies including:
• Food effect studies
• Dosage Regimen assessments
• Diabetic Clamp studies
• QTc studies
• First in man, dose escalation, PK/PD
• Multiple dose studies
• Drug interaction studies
• Bioavailability, bioequivilence
• Phase I patient studies
• Special population studies
• Patient studies
• Special population studies
• Proof of concept studies
jobs

Roles in this area at ICON

Label Project Coordinator

Salary

Location

West Point

Department

Regulatory, Drug Safety/ Quality Assurance & Other roles

Location

West Point

Remote Working

Office Based

Business Area

ICON Strategic Solutions

Job Categories

Logistics & Supplies

Job Type

Permanent

Description

As a Label Project Coordinator you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.  This role will require 2/3 day onsite i

Reference

2025-119364

Expiry date

01/01/0001

Brandon Pupek

Author

Brandon Pupek
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Clinical Research Associate - Oncology - Northeast

Salary

Location

United States

Department

Clinical Monitoring

Location

United States

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a Clinical Research Associate you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-119309

Expiry date

01/01/0001

Monica Hawkins Read more Shortlist Save this role
CRA II- FL

Salary

Location

United States

Department

Clinical Monitoring

Location

United States

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a CRA II you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-119323

Expiry date

01/01/0001

Kala Murphy

Author

Kala Murphy
Kala Murphy

Author

Kala Murphy
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Clinical Research Associate II- Nebraska

Salary

Location

United States

Department

Clinical Monitoring

Location

United States

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a CRA II you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-117742

Expiry date

01/01/0001

Kala Murphy

Author

Kala Murphy
Kala Murphy

Author

Kala Murphy
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CRA II- PA/NJ/NY/MA

Salary

Location

United States

Department

Clinical Monitoring

Location

United States

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a CRA II you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-119321

Expiry date

01/01/0001

Kala Murphy

Author

Kala Murphy
Kala Murphy

Author

Kala Murphy
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Senior CRA- FL

Salary

Location

United States

Department

Clinical Monitoring

Location

United States

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a Senior CRA you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-119315

Expiry date

01/01/0001

Kala Murphy

Author

Kala Murphy
Kala Murphy

Author

Kala Murphy
Read more Shortlist Save this role
CRA II- PA/NJ/NY/MA

Salary

Location

United States

Department

Clinical Monitoring

Location

United States

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a CRA II you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-119319

Expiry date

01/01/0001

Kala Murphy

Author

Kala Murphy
Kala Murphy

Author

Kala Murphy
Read more Shortlist Save this role
CRA II- Nebraska

Salary

Location

United States

Department

Clinical Monitoring

Location

United States

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a CRA II you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-119292

Expiry date

01/01/0001

Kala Murphy

Author

Kala Murphy
Kala Murphy

Author

Kala Murphy
Read more Shortlist Save this role
Clinical Research Associate - Oncology - California

Salary

Location

United States

Department

Clinical Monitoring

Location

United States

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a Clinical Research Associate you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-119487

Expiry date

01/01/0001

Monica Hawkins Read more Shortlist Save this role
Executive Director, Sales Training & Enablement

Salary

Location

US, Blue Bell (ICON)

Department

Full Service - Commercial Solutions

Location

Blue Bell

Remote Working

Hybrid: Office/Remote

Business Area

ICON Full Service & Corporate Support

Job Categories

Business Development

Job Type

Permanent

Description

Location: US / UKReports To: Chief Commercial OfficerPosition Overview: The Exec Dir of Sales Training and Enablement will be responsible for developing and executing strategies that enhance the skill

Reference

JR130338

Expiry date

01/01/0001

Christopher Frank Read more Shortlist Save this role
Senior CRA - Bilingual

Salary

Location

Canada

Department

Clinical Monitoring

Location

Canada

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us

Reference

2025-117365

Expiry date

01/01/0001

Jamie Pruitt

Author

Jamie Pruitt
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Clinical Research Associate - Oncology - Northeast

Salary

Location

Philadelphia, United States, Boston

Department

Clinical Monitoring

Location

Boston

Philadelphia

United States

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a Clinical Research Associate you will be joining the world’s largest & most comprehensive clinical research organisation, powered by healthcare intelligence.

Reference

2025-119124

Expiry date

01/01/0001

Monica Hawkins Read more Shortlist Save this role
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Ovarian cancer knot being held in woman's hands
Standing Strong on Ovarian Cancer Day

Teaser label

Inside ICON

Content type

Blogs

Publish date

05/08/2025

Summary

Standing Strong on Ovarian Cancer Day:    ICON's Commitment to Advancing Care Ovarian cancer remains one of the most challenging gynaecologic malignancies, both in terms of detection and treatmen

Teaser label

Martin Lachs, VP, Oncology Project Management at ICON discusses ICON’s role in advancing ovarian cancer research.

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Nurse and patient
Patient Centricity in Clinical Research

Teaser label

Industry

Content type

Blogs

Publish date

05/07/2025

Summary

Patient Centricity in Clinical Research: What it is and Why it Matters In the past, clinical research was designed around the needs of sponsors, researchers, and regulatory bodies. Patients were of

Teaser label

Discover how patient centricity is reshaping clinical research by placing participants at the heart of study design and execution.

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Navigating Regulatory Landscapes - FDA, EMA, & MHRA

Teaser label

Industry

Content type

Blogs

Publish date

05/05/2025

Summary

Navigating Regulatory Landscapes:     Comparing FDA, EMA, & MHRA in Clinical Trials In clinical research, no matter how promising a new therapy may be, it will go nowhere without regulatory appro

Teaser label

Compare FDA, EMA, and MHRA regulatory frameworks for clinical trials, and why this knowledge matters.

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