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Early Phase Services

Strategy & delivery of early-phase clinical development services

Preclinical/Phase 1 specialise in the strategy and delivery of early-phase clinical development services. This enables us to provide informed, timely decisions for our clients.

Our Development Solutions teams have expertise in early phase clinical research, bioanalytics, PK-PD modelling and simulation as well as the full range of supporting services. In everything we do we incorporate scientific excellence and product development strategy.

Our experts are multi-disciplinary and have the experience to address even the most demanding of drug development challenges with an uncompromising focus on completing projects on time, within budget and to a standard that will always shine under even the most critical scrutiny.


In this area our key services include:

• Product development consulting
• Bioanalytical
• PK/PD Modelling and simulation
• Population PK
• Data Analysis (TK, PK, PK/PD)
• Regulatory affairs strategy / submission
• Protocol design 
• Medical Writing
• Quality Control/Assurance
• Pharmacodynamic Models
• Clinical studies including:
• Food effect studies
• Dosage Regimen assessments
• Diabetic Clamp studies
• QTc studies
• First in man, dose escalation, PK/PD
• Multiple dose studies
• Drug interaction studies
• Bioavailability, bioequivilence
• Phase I patient studies
• Special population studies
• Patient studies
• Special population studies
• Proof of concept studies
jobs

Roles in this area at ICON

Study Start Up Associate II

Salary

Location

Mexico, Mexico City

Location

Sao Paulo

Mexico City

Remote Working

Office or Home

Business Area

ICON Full Service & Corporate Support

Job Categories

Study Start Up

Job Type

Permanent

Description

We are currently seeking a Study Start Up Associate II to join our diverse and dynamic team. As a Study Start Up Associate II at ICON, you will play a pivotal role in leading the initiation of clinica

Reference

JR133973

Expiry date

01/01/0001

Diego  Tonini

Author

Diego Tonini
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Manager, Clinical Operations - Start-Up (FSP - Sponsor Dedicated)

Salary

Location

Brazil, Sao Paulo

Location

Sao Paulo

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Operations Management

Job Type

Permanent

Description

We are currently seeking a Manager, Clinical Operations to oversee start up function dedicated to ISS client. As a Manager, Clinical Operations at ICON, you will play a pivotal role in overseeing the

Reference

JR135596

Expiry date

01/01/0001

Simone Chan

Author

Simone Chan
Simone Chan

Author

Simone Chan
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EDC Developer

Salary

Location

Canada, Burlington

Location

Burlington

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Systems

Job Type

Permanent

Description

We are currently seeking a Senior EDC Developer to join our diverse and dynamic team. As a Senior Clinical System Designer at ICON, you will play a pivotal role in designing and implementing advanced

Reference

JR136621

Expiry date

01/01/0001

Brendan Hoey

Author

Brendan Hoey
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Associate Director, BOSE - Process, Training & Execution

Salary

Location

Regional United States (PRA)

Location

Multiple US Locations

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Quality Assurance

Job Type

Permanent

Description

We are currently seeking a Senior Manager Quality Assurance to join our diverse and dynamic team. As a Senior Manager Quality Assurance at ICON, you will play a pivotal role in ensuring the quality an

Reference

JR136281

Expiry date

01/01/0001

Brendan Hoey

Author

Brendan Hoey
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Medical Research Associate (Medical Assistant/Phlebotomist)-

Salary

Location

US, San Antonio, TX, IDS

Location

San Antonio

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinic

Job Type

Temporary Employee

Description

We are currently seeking a Medical Research Associate to join our diverse and dynamic team. As an MRA at ICON, you will support the design, execution, and management of clinical trials and research st

Reference

JR135992

Expiry date

01/01/0001

Stephanie Curran Read more Shortlist Save this role
Senior Clinical Research Associate - Quebec

Salary

Location

Canada

Department

Clinical Monitoring

Location

Canada

Remote Working

Remote

Business Area

ICON Strategic Solutions

Job Categories

Clinical Monitoring

Job Type

Permanent

Description

As a CRA you will be joining the world’s largest & most comprehensive clinical research organization, powered by healthcare intelligence. En tant qu’ARC (Associé(e) de recherche clinique), vous rejoin

Reference

2025-121578

Expiry date

01/01/0001

Jamie Pruitt

Author

Jamie Pruitt
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Clinical Imaging Analyst

Salary

Location

Portugal, Lisbon

Department

Full Service - Development & Commercialisation Solutions

Location

Dublin

Lisbon

Remote Working

Office or Home

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Data Management

Job Type

Permanent

Description

We are currently seeking a Clinical Data Analyst to join our dynamic Medical Imaging and Cardiac Safety team at ICON. In this role, you will be instrumental in ensuring data accuracy and quality for i

Reference

JR133872

Expiry date

01/01/0001

James Smith

Author

James Smith
James Smith

Author

James Smith
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Data & Reporting Analyst II

Salary

Location

India, Chennai

Department

Full Service - Corporate Support

Location

Chennai

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Analyst

Job Type

Permanent

Description

At ICON, it’s our people that set us apart. Our diverse teams enable us to become a better partner to our customers and help us to fulfil our mission to advance and improve patients’ lives. Our ‘Own I

Reference

JR135504

Expiry date

01/01/0001

Puja Jaiswal

Author

Puja Jaiswal
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Senior Site Management Associate

Salary

Location

Romania, Bucharest

Department

Real World Solutions

Location

Warsaw

Bucharest

Barcelona

Madrid

Gdansk

Remote Working

Office or Home

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

We are currently seeking a Senior Site Management Associate to join our diverse and dynamic team. As a Senior Site Management Associate at ICON, you will play a critical role in overseeing site manage

Reference

JR134304

Expiry date

01/01/0001

Teodora  Kaykieva Read more Shortlist Save this role
Senior Clinical Trial Manager

Salary

Location

Mexico, Mexico City

Department

Clinical Trial Management

Location

Buenos Aires

Sao Paulo

Santiago

Mexico City

Remote Working

Office or Home

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Trial Management

Job Type

Permanent

Description

We are currently seeking a Senior Clinical Trial Manager to join our diverse and dynamic team. As the Senior Clinical Trial Manager, you will hold a crucial role in ensuring the successful delivery of

Reference

JR134206

Expiry date

01/01/0001

Katty Barreto Maia Read more Shortlist Save this role
IHCRA

Salary

Location

France, Paris

Department

Clinical Monitoring

Location

Paris

Remote Working

Office Based

Business Area

ICON Full Service & Corporate Support

Job Categories

Clinical Trial Support

Job Type

Permanent

Description

As an In-House Clinical Research Associate (IHCRA), you will support our global pharmaceutical clients, with whom ICON shares a culture of innovation, flexibility, and a common vision: bringing to mar

Reference

JR132369

Expiry date

01/01/0001

Sophie Clarke

Author

Sophie Clarke
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Inside ICON Bulgaria: Career Insights from Dimitar Karzhin, Site Head

Teaser label

Our People

Content type

Blogs

Publish date

10/08/2025

Summary

A Career Built on Purpose: Dimitar's Journey at ICON Plc Dimitar Karzhin’s career path is not one he could have predicted. What began with a decade as a practicing General Practitioner in Bulgaria l

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Discover valuable career insights and leadership lessons from Dimitar Karzhin, Site Head of ICON Plc Bulgaria.

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10 Steps to Building a Professional LinkedIn Profile

Teaser label

Career Progression

Content type

Blogs

Publish date

09/19/2025

Summary

How to Build a Strong LinkedIn Profile That Attracts Employers LinkedIn is no longer just a digital CV. It is a professional network, a space to showcase your skills and a platform to connect with

Teaser label

Discover practical tips on creating a professional profile, networking effectively and growing your career online.

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Shaping a Career in Clinical Research

Teaser label

Our People

Content type

Blogs

Publish date

09/16/2025

Summary

Growing with ICON: Christina’s Journey in Clinical Operations and Quality Leadership At ICON, we are proud to showcase the incredible journeys of our colleagues who make a real impact on pati

Teaser label

Read about Christina’s journey from CRA to Clinical Operations Manager at ICON Strategic Solutions.

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